MtoZ Biolabs' C18 Spin Columns enable rapid peptide desalting and cleanup to remove MS incompatible salts detergents and other interferents, improving spectral quality and sequence coverage in MALDI and ESI based workflows.
Product Overview
Traditional approaches for peptide cleanup can be slow and inconsistent, and they often trade contaminant removal for peptide recovery. Common challenges of peptide cleanup include:
1. Too Many Handling Steps
Multiple transfers and repeated processing increase the chance of sample loss and operator to operator variability.
2. Low and Inconsistent Recovery
Peptides can be lost during cleanup or fail to elute efficiently, which is especially problematic for low input or low abundance samples.
3. Hard to Scale for Parallel Samples
Processing many samples at once can be cumbersome, making it difficult to keep timing and conditions consistent across batches.
4. Limited Tolerance for Different Loads
Workflows may require tight control of sample volume or concentration, adding extra steps and increasing variability.
Advantages
✔️Efficient Interferent Removal
Optimized C18 binding and washing conditions clear a broad range of reverse phase compatible contaminants, supporting higher signal to noise and cleaner chromatograms.
✔️Flexible Loading Without Pre Concentration
The product accommodates a wide range of sample volumes and concentrations, reducing the need to evaporate or concentrate prior to cleanup.
✔️Convenient Parallel Processing
Spin column handling enables fast multi sample processing with standard centrifugation, improving throughput and consistency.
✔️High Recovery
MtoZ Biolabs' C18 Spin Columns use high performance C18 resin to support strong peptide recovery even when starting material is limited, helping preserve sensitivity for downstream analyses.
Technical Support
1. Protocol Downloads
MtoZ Biolabs provides comprehensive experimental protocols and product manuals to help ensure smooth and reproducible workflows. For access to specific documents or detailed instructions, please contact our support team.
2. Customized Service Support
Our experienced scientists offer tailored technical assistance and customized solutions based on your specific research goals, helping you achieve optimal experimental outcomes.
3. FAQ and Expert Assistance
We provide responsive and professional technical support to address your questions efficiently. Our experts are ready to help you identify and resolve experimental challenges quickly and accurately.
