Protein Sequence Analysis

Protein primary sequence determines the advanced structure of a protein, influencing a protein’s function. Therefore, it is essential to analyze the sequence of a protein, to verify the integrity and correct translation of a protein sample. MtoZ Biolabs has developed a comprehensive protein sequencing platform to meet various needs of our clients, from N-terminal and C-terminal sequencing to full-length and de novo sequencing. Our featured services are presented below, but if you have any special requirement, you are welcome to contact us for custom service.

Service Categories




Protein De novo sequencing

De novo sequencing for analyzing sequences of novel protein, peptides, and antibodies, of which database information is not available.

 



Protein N-Terminal Sequencing

Accurate determination of N-terminal sequence of proteins and peptides, ensured by a combination of Edman Degradation Sequencing system and N-terminal De novo Sequencing technique.

 



Protein C-Terminal Sequencing

Comprehensive protein C-terminal integrity analysis, including sequence analysis, PTMs, and C-terminal truncation evaluation, based on high-resolution LC-MS/MS technology.

 



Protein Edman Degradation

Automatic Edman Degradation Sequencing system, equipped with HPLC technology, allowing analyzing over 30 amino acids at protein N-terminus.

 



Protein Full-length Sequencing

Using LC-MS/MS technology and 6 digestive enzymes, MtoZ Biolabs provides true full-length sequencing service. Accurate sequence analysis and 100% of protein sequence coverage is guaranteed.

Related Services

Protein Sequencing

Protein De Novo Seq
N-Terminal Sequencing
C-Terminal Sequencing
Edman Degradation
Protein Full-length Sequencing



Protein Analysis

Protein Identification
Protein Mass Measurement
LC-MS Analysis of Pull-down Proteins
Native MS Analysis



PTM Analysis

Phospho-proteomics
Acetyl-proteomics
Ubiquitin-proteomics
Glyco-proteomics
Disulfide bond
Histone Modifications

• • Sequencing of Unknown Proteins

  The amino acid sequence of proteins forms the basis for determining protein structure and function. Protein sequencing, which determines the types

• • Protein Mutation Analysis

  Protein mutation refers to the alteration in the amino acid composition or sequence of a protein, which subsequently leads to changes in the struc

• • Sequence Analysis Based on Mass Spectrometry

  Mass spectrometry-based sequence analysis of proteins, antibodies, peptides, and other samples involves the analysis of the sample's amino acid se

• • N-Terminal Sequencing

  MtoZ Biolabs provides protein n terminal sequencing service, which solves problems of N terminal blockage and PTMs.

• • C-Terminal Sequencing

  MtoZ Biolabs have developed a LC-MS/MS system, which is suitable for analyzing both N- and C-terminal amino acid sequence and PTMs.

• • Edman Degradation

  MtoZ Biolabs provide automatic and accurate N-terminal Edman sequencing service, based on HPLC and SHIMADZU PPSQ-33A Analyzer.

• • PCR based Antibody Sequencing

  MtoZ Biolabs provides accurate and cost effective antibody gene sequencing services, based on degenerate primer design and PCR amplification techn