The BS3 (sulfo-DSS), No-Weigh Format from MtoZ Biolabs is a high-purity, membrane-permeable crosslinker designed for efficient covalent protein-protein interaction studies, biological conjugation, and protein complex stabilization in a simplified, ready-to-use format.
Product Overview
BS3 (sulfo-DSS) is an effective crosslinker for protein-protein interaction studies, but its use in experiments can present the following challenges:
1. Inefficient Crosslinking
Low-quality or poorly reactive crosslinkers lead to non-specific interactions or incomplete capture of target proteins.
Many crosslinkers cannot penetrate cell membranes, restricting their use for intracellular protein studies.
3. Weighing Errors
Powdered crosslinkers require precise weighing, which can be error-prone and affected by humidity.
4. Limited Flexibility
Standard crosslinkers may not meet varying hydrophobic or hydrophilic requirements for different experimental setups.
Advantages
The MtoZ Biolabs BS3 (sulfo-DSS), No-Weigh Format offers the following benefits:
✅ High Purity and Reactivity
BS3 features NHS ester groups that react efficiently with primary amines to form stable amide bonds, ensuring high specificity and crosslinking efficiency.
✅ Membrane Permeability
As a hydrophobic crosslinker, BS3 penetrates cell membranes, enabling intracellular crosslinking and the capture of transient or weak protein interactions.
✅ Convenient Pre-Packaged Format
The No-Weigh format eliminates the need for weighing, reducing measurement errors and simplifying the process for consistent results.
✅ Versatility for Various Applications
Ideal for protein-protein interaction studies, in situ crosslinking, and protein conjugation in both cell lysates and intact cells.
Technical Support
1. Protocol Downloads
MtoZ Biolabs provides comprehensive experimental protocols and product manuals to help ensure smooth and reproducible workflows. For access to specific documents or detailed instructions, please contact our support team.
2. Customized Service Support
Our experienced scientists offer tailored technical assistance and customized solutions based on your specific research goals, helping you achieve optimal experimental outcomes.
3. FAQ and Expert Assistance
We provide responsive and professional technical support to address your questions efficiently. Our experts are ready to help you identify and resolve experimental challenges quickly and accurately.
