MtoZ Biolabs Immunoenrichment Kits - Targeting the Core of Antigen Presentation, Enabling Efficient Capture of MHC Peptides and Providing a Critical Foundation for Tumor Immunology and Vaccine Development
Immunopeptides presented by MHC molecules serve as the molecular link between intracellular protein states and adaptive immune responses. Comprehensive characterization of these peptides is essential for understanding immune surveillance, developing neoantigen-based vaccines, and advancing innovative immunotherapeutic strategies. MtoZ Biolabs Immunoenrichment Kits are specifically engineered for the efficient enrichment of extremely low-abundance and highly hydrophobic MHC peptides, offering an integrated solution for high-sensitivity and high-specificity isolation and purification from cell or tissue samples. This platform enables accurate mapping of the immunopeptidome and facilitates in-depth investigation of immune recognition mechanisms.
Advantages
High Specificity and Low Background
Based on high-affinity antibodies or engineered receptors, MtoZ Biolabs Immunoenrichment Kits enable the specific capture of defined classes of MHC molecules (such as HLA-I and HLA-II), thereby effectively minimizing nonspecific binding and sample-derived background interference.
Ultra-High Sensitivity
The optimized enrichment workflow and elution conditions allow efficient recovery of low-abundance immunopeptides at the nanogram- to picogram-level, fulfilling the analytical requirements of precious clinical specimens (such as tumor tissues).
Broad Sample Compatibility
The method is applicable to a wide range of sample types, including cultured cells, fresh or frozen tissues, and plasma samples, thereby supporting comprehensive applications spanning from basic research to clinical translation.
Direct Compatibility with Mass Spectrometry Analysis
The enriched peptides exhibit high purity with extremely low residual levels of salts and detergents, enabling direct high-resolution identification by liquid chromatography–tandem mass spectrometry (LC-MS/MS) and ensuring reliable data quality.
Technical Support
Protocol Downloads
MtoZ Biolabs provides comprehensive experimental protocols and product manuals to help ensure smooth and reproducible workflows. For access to specific documents or detailed instructions, please contact our support team.
Customized Service Support
Our experienced scientists offer tailored technical assistance and customized solutions based on your specific research goals, helping you achieve optimal experimental outcomes.
FAQ and Expert Assistance
We provide responsive and professional technical support to address your questions efficiently. Our experts are ready to help you identify and resolve experimental challenges quickly and accurately.
- HLA Class II Immunopeptide Enrichment KitQuantity: 24 reactions
- HLA Class I Immunopeptide Enrichment KitQuantity: 24 reactions
- Human MHC Class I Peptide Enrichment KitQuantity: 24 reactions