MtoZ Biolabs Water, LC-MS Grade is an ultra-pure water product specifically designed for LC-MS/UHPLC-MS applications. It undergoes stringent purification and lot-to-lot quality control verification to significantly reduce background interference and improve the stability and reproducibility of both chromatographic and mass spectrometric data.
Product Overview
In high-sensitivity LC-MS analysis, the aqueous phase is often an “invisible variable,” where trace impurities can quickly translate into noise and false-positive signals:
1. Background Contamination Is Hard to Detect
Trace organic compounds and extractables can raise the baseline and generate ghost peaks, interfering with qualitative and quantitative analysis of target analytes.
2. Metal Ions Cause Adducts and Memory Effects
Sodium, potassium, and trace metals can form adduct peaks, reduce ionization efficiency, and increase carryover risk.
3. UV Absorbance and Nonvolatile Residue Affect Separation and Detection
Insufficient UV transparency or elevated evaporation residue can compromise UHPLC-UV baseline stability and peak identification.
4. Batch Variability Undermines Method Reproducibility
Differences in water quality across sources can lead to retention time drift and response fluctuations, reducing alignment and comparability in large-cohort studies.
5. Higher Stability Demands When Switching Ionization Modes
In ESI/APCI and in both positive and negative ion modes, water cleanliness directly impacts signal stability and result consistency.
Advantages
✅ LC-MS Suitability Verified
Performance-tested and lot QC qualified for LC-MS workflows, supporting high-sensitivity analysis while minimizing potential interferences.
✅ Ultra-Low Metal and Ionic Background
Helps reduce metal-adduct formation and ion suppression, improving spectral interpretability and quantitative reliability.
✅ Low UV Absorbance and Low Evaporation Residue
Enhances UHPLC-UV baseline cleanliness and stability, supporting high-resolution method development.
✅ Microfiltration for Improved Cleanliness
Filtered through a microporous membrane to reduce particulates and micro-contaminants that can cause pressure instability and system noise.
✅ Compatible with Multiple Ionization Modes
Suitable for ESI/APCI and both positive and negative ion modes, enabling faster, more reliable, and highly reproducible results.
Technical Support
1. Protocol Downloads
MtoZ Biolabs provides comprehensive experimental protocols and product manuals to help ensure smooth and reproducible workflows. For access to specific documents or detailed instructions, please contact our support team.
2. Customized Service Support
Our experienced scientists offer tailored technical assistance and customized solutions based on your specific research goals, helping you achieve optimal experimental outcomes.
3. FAQ and Expert Assistance
We provide responsive and professional technical support to address your questions efficiently. Our experts are ready to help you identify and resolve experimental challenges quickly and accurately.
