The Cytokines from MtoZ Biolabs are high-purity, high-activity recombinant cytokines that provide reliable tools for immunology research, cell biology studies, and drug discovery.
Product Overview
When conducting cytokine-based functional assays, researchers frequently encounter several technical and experimental challenges:
1. Insufficient Purity and Interference from Impurities
Crude or low-purity cytokine preparations may contain endotoxins, host cell proteins, or other contaminants that can trigger non-specific cell activation or cytotoxic effects, ultimately compromising data reliability and biological interpretation.
2. Unstable Bioactivity and Batch-to-Batch Variability
Cytokines are inherently prone to degradation and loss of activity. Inadequate storage conditions or inconsistent manufacturing processes can lead to reduced potency, poor reproducibility, and difficulty in establishing consistent dose-response relationships.
3. Incomplete Functional Validation
Some commercially available cytokines provide only nominal concentration information without robust biological activity data. As a result, users must perform time-consuming and sample-intensive activity titration and validation experiments independently.
4. Species Specificity and Formulation Limitations
Cytokine signaling is often species-specific, requiring precise matching between experimental models and cytokine origin. In addition, many products lack optimized storage buffers, necessitating additional handling steps that increase experimental complexity and the risk of protein denaturation.
Advantages
✅ Ultra-High Purity With Extremely Low Endotoxin Levels
MtoZ Biolabs’ Cytokines are produced using advanced expression and purification technologies, achieving purities greater than 95% with exceptionally low endotoxin levels (typically <1.0 EU/μg). This minimizes non-specific effects caused by contaminants and ensures both experimental specificity and cellular safety.
✅ Rigorous Activity Validation for Reliable Performance
Each batch of MtoZ Biolabs Cytokines is stringently tested using standardized biological activity assays, such as reporter gene systems or cell proliferation/inhibition assays, with ED₅₀ values determined. Detailed activity units and specific activity data are provided to ensure stable, potent bioactivity and highly reproducible experimental outcomes.
✅ Ready-to-Use Formulations for Convenient Storage and Handling
MtoZ Biolabs offers Cytokines in either lyophilized form or stabilized, ready-to-use liquid formulations. These formulations are carefully optimized to maintain long-term stability. Clear reconstitution guidelines and storage recommendations are provided to support efficient experimental planning and sample management.
✅ Broad Species Coverage and Flexible Selection
MtoZ Biolabs provides Cytokines derived from multiple commonly used species, including human, mouse, and rat. For many cytokines, multiple isoforms or engineered variants are available, enabling cross-species comparative studies and precise modulation of specific signaling pathways.
Technical Support
1. Protocol Downloads
MtoZ Biolabs provides comprehensive experimental protocols and product manuals to help ensure smooth and reproducible workflows. For access to specific documents or detailed instructions, please contact our support team.
2. Customized Service Support
Our experienced scientists offer tailored technical assistance and customized solutions based on your specific research goals, helping you achieve optimal experimental outcomes.
3. FAQ and Expert Assistance
We provide responsive and professional technical support to address your questions efficiently. Our experts are ready to help you identify and resolve experimental challenges quickly and accurately.