The Hamster (CHO) PLBL2 ELISA Kit developed by MtoZ Biolabs is specifically designed for the quantitative detection of PLBL-2 impurities in CHO expression systems. It features high sensitivity and good specificity and can be used to evaluate the purification performance of biopharmaceutical products.
Product Overview
In CHO cell expression systems, PLBL-2 is a host cell-derived residual protein with low abundance and a complex background. Its detection in recombinant protein purification samples presents specific challenges for residual analysis:
1. Low and Variable Residual Levels
The residual level of PLBL-2 is low at different purification stages and fluctuates significantly with process variations, making it difficult for conventional detection methods to consistently cover the low concentration range.
2. Complex Sample Matrix
Purified samples may still contain high-abundance target proteins and buffer components, which can interfere with signal interpretation of the target residual protein.
3. High Difficulty in Specific Discrimination
PLBL-2 coexists with other CHO host cell proteins, and without specific detection approaches, non-target signal interference can easily occur.
4. High Requirements for Quantitative Consistency
Residual analysis requires consistent and comparable results across different batches, placing high demands on the stability and reproducibility of the detection method.
Advantages
✅ High-Specificity Recognition
The kit employs an immunorecognition system targeting PLBL-2, enabling effective discrimination of the target residual protein from other host cell proteins and reducing the risk of nonspecific reactions.
✅ Low-Level Detection Capability
The Hamster (CHO) PLBL2 ELISA kit from MtoZ Biolabs is suitable for samples containing low levels of PLBL-2 residues and can stably reflect subtle changes during the purification process.
✅ Matrix Interference Tolerance
The optimized detection system minimizes the impact of high-abundance proteins and buffer components on the results, improving detection reliability under complex sample conditions.
✅ Stable and Reproducible Results
Standardized ELISA procedures and quality control design help ensure consistency of detection results across different experimental batches, meeting the requirements for continuous residual monitoring.
Technical Support
1. Protocol Downloads
MtoZ Biolabs provides comprehensive experimental protocols and product manuals to help ensure smooth and reproducible workflows. For access to specific documents or detailed instructions, please contact our support team.
2. Customized Service Support
Our experienced scientists offer tailored technical assistance and customized solutions based on your specific research goals, helping you achieve optimal experimental outcomes.
3. FAQ and Expert Assistance
We provide responsive and professional technical support to address your questions efficiently. Our experts are ready to help you identify and resolve experimental challenges quickly and accurately.
