Disease-Focused Exosome Research Service
- Ultracentrifugation
- Microfluidic device
- Size exclusion chromatography (SEC)
- Polymer-based precipitation
- Immunoaffinity capture
- Nanoparticle tracking analysis (NTA)
- Transmission electron microscope (TEM)
- Western blotting
- Flow cytometry
- Fluorescent labeling
- Bioluminescence imaging (BLI)
- Magnetic resonance imaging (MRI)
- Computed tomography (CT)
- Animal models
- Genetic engineering
- Electroporation
- Chemical conjugation
- Sonication
- Genetic editing
- Metabolic labeling
- Biomarker discovery for early disease diagnosis and prognosis
- Therapeutic development, including exosome-based delivery systems
- Mechanistic research to explore cell–cell communication in disease models
- Patient stratification and treatment response monitoring
- Regenerative medicine using engineered exosomes as therapeutic tools
- Immune regulation in infection, cancer, and autoimmunity contexts
Exosomes are nanosized extracellular vesicles secreted by nearly all cell types under physiological and pathological conditions. These vesicles carry diverse bioactive cargoes, including proteins, lipids, mRNA, microRNA, long non-coding RNA, and DNA fragments, which reflect the state and origin of their parent cells. Increasing evidence has revealed that exosomes play essential roles in intercellular communication, disease progression, immune modulation, and tissue remodeling. Their ability to cross biological barriers and remain stable in biofluids makes them ideal candidates for biomarker discovery, therapeutic development, and drug delivery.
Figure 1. The Biogenesis, Contents, and Internalization of Exosomes
Recognizing the importance of disease-specific exosome research, MtoZ Biolabs has developed a dedicated Disease-Focused Exosome Research Service. Our Disease-Focused Exosome Research Service platform provides comprehensive support for the isolation, characterization, profiling, and functional analysis of exosomes derived from a wide range of disease models and patient samples. This service is designed to help researchers understand disease mechanisms, identify diagnostic and prognostic biomarkers, and develop exosome-based therapeutic strategies.
Service at MtoZ Biolabs
Disease-Focused Exosome Research Solution at MtoZ Biolabs
1️⃣Cancer Exosome Research Service
Cancer-derived exosomes promote tumor growth, immune evasion, angiogenesis, metastasis, and chemoresistance. We analyze the molecular cargo of tumor exosomes to identify biomarkers, explore intercellular signaling pathways, and assess therapeutic targets across various cancer types.
2️⃣Neurological Disease Exosome Research Service
Exosomes in neurological diseases such as Alzheimer’s, Parkinson’s, Huntington’s disease, and stroke participate in both pathological propagation (e.g., amyloid-β, tau, α-synuclein) and neuroprotective signaling. Due to their ability to cross the blood-brain barrier and circulate in peripheral biofluids, brain-derived exosomes offer a noninvasive window into central nervous system (CNS) pathology. Our service enables researchers to track brain-derived exosomes, discover CNS biomarkers, and evaluate the therapeutic potential of engineered vesicles.
3️⃣Cardiovascular Disease Exosome Research Service
In cardiac pathology, exosomes regulate apoptosis, fibrosis, angiogenesis, and immune responses. We support cardiovascular studies by profiling disease-specific exosomes from cardiomyocytes, stem cells, and patient-derived samples to understand heart failure, myocardial infarction, and vascular disorders.
4️⃣Tissue Regeneration and Repair Exosome Research Service
Stem cell-derived exosomes have regenerative effects by modulating inflammation, fibrosis, and cellular proliferation. We offer analytical and functional solutions for characterizing therapeutic exosomes used in tissue engineering and regenerative medicine applications.
5️⃣Infectious Disease Exosome Research Service
Exosomes act as mediators of host-pathogen communication. They may carry viral proteins or RNAs, modulate immune responses, or facilitate pathogen spread. We enable in-depth investigation of pathogen-associated and host-derived exosomes in viral, bacterial, and parasitic infections.
6️⃣Kidney Disease Exosome Research Service
Exosomes have emerged as critical players in various kidney conditions, including acute kidney injury, lupus nephritis, diabetic nephropathy, renal fibrosis, and chronic kidney disease. They contribute to disease progression by mediating inflammatory and fibrotic signaling but also serve as reservoirs of diagnostic information. Urinary exosomes, in particular, provide accessible, noninvasive biomarkers that reflect renal cellular states. Moreover, their therapeutic potential is being explored for modulating renal repair and immune responses. Our service supports in-depth characterization and functional assessment of kidney-derived exosomes to advance biomarker discovery and targeted therapy development.
Comprehensive Exosome Analysis Services by MtoZ Biolabs
💠Exosome Isolation and Purification
Using advanced techniques, we ensure the isolation of high-purity and intact exosomes from blood, serum, tissue, or cell culture media.
We provide comprehensive analysis of physical characterization and exosome markers (CD63, CD81, TSG101, etc.).
💠Exosomal Cargo Profiling
We conduct in-depth analysis of proteins (LC-MS/MS), RNAs (miRNA/lncRNA/circRNA-seq), metabolites, and lipids to define functional signatures and biomarker candidates.
💠Exosomes Labeling and Tracking
Our service supports exosome labeling and real-time tracking to investigate cell-specific exosome origin, cargo loading mechanisms, and downstream biological effects.
We conduct in vitro and in vivo functional assays to determine the effects of exosomes.
Our team supports exosome modification to deliver therapeutic RNAs or proteins into target cells, advancing medical research.
Analysis Workflow
Service Advantages
☑️Advanced Analysis Platform: MtoZ Biolabs established an advanced Disease-Focused Exosome Research Service platform, guaranteeing reliable, fast, and highly accurate analysis service.
☑️Customizable and Scalable Solutions: Offers flexible study designs tailored to specific disease models, sample types, and research goals.
☑️Expert Scientific Support: Backed by a team of experienced scientists with deep expertise in exosome biology and disease mechanisms.
☑️End-to-End Workflow: From exosome isolation to in-depth functional and molecular profiling, all conducted under rigorous quality control.
Applications
Our Disease-Focused Exosome Research Service has broad applications, including:
Sample Submission Suggestions
*Please consult us for tailored sample collection and storage protocols to maximize data quality.
Deliverables
1. Comprehensive experimental details (materials, instruments, and methods)
2. Raw data
3. Processed omics data files
4. Quality control reports (NTA, Western blot, TEM images)
5. Functional assay results
6. Bioinformatics analysis
7. Customized report based on project requirements
Our Disease-Focused Exosome Research Service is designed to provide more rapid, high-throughput, and cost-effective analysis, with exceptional data quality and minimal sample consumption. Free project evaluation, welcome to learn more details.
Related Services
Exosomal Biogenesis and Identification Service
Exosomal Cargo and Loading Mechanism Service
Exosome-Based Drug Delivery Service
Exosome Antibody Development Service
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