Exosome Analysis Services
Exosomes are nanoscale extracellular vesicles (EVs) originating from multivesicular bodies (MVBs), typically measuring 30–150 nm in diameter. They are widely distributed in body fluids such as blood, urine, saliva, and cerebrospinal fluid. By encapsulating and transporting bioactive molecules, including proteins, lipids, DNA, mRNA, miRNA, lncRNA, and circRNA, exosomes play key roles in intercellular communication, immune regulation, tumor microenvironment remodeling, tissue regeneration, and disease progression. As such, exosomes have emerged as vital carriers for biomarker discovery, disease diagnosis, and targeted therapy development.
Contreras-Naranjo, JC. et al. Lab Chip. 2017.
Systematic exosome analysis not only helps elucidate their origin, molecular contents, and biological functions, but also supports a full spectrum of research from basic science to translational applications. Especially in liquid biopsy, neurodegenerative diseases, early cancer screening, and nanomedicine development, exosome profiling has become a critical component of high-throughput omics and functional studies.
Leveraging cutting-edge multi-omics platforms, robust bioinformatics pipelines, and stringent quality control systems, MtoZ Biolabs has established a comprehensive Exosome Analysis Services covering exosome separation and purification, exosome profiling, exosome characterization, exosomics analysis, and more, offering an all-in-one solution for researchers and biotech innovators worldwide.
Services at MtoZ Biolabs
MtoZ Biolabs’ Exosome Analysis Services comprises seven major modules, covering the full workflow from raw sample processing to downstream functional application:
1. Exosome Separation & Purification Service
This service supports a wide range of sample sources, including Animal Cell, Body Fluid, Plant, Microorganism, and Tissue by the menas of multiple purification strategies such as Ultracentrifugation and Microfiltration, Size Exclusion Chromatography (SEC), and Immunoaffinity Capture. High-purity exosomes can be efficiently isolated and prepared for downstream RNA, protein, cfDNA, and cytokine analysis.
2. Exosome Characterization Service
MtoZ Biolabs utilizes multiple advanced technologies to support comprehensive exosome characterization, including size measurement, structural analysis, surface marker validation, and component identification. The platform integrates Nanoparticle Tracking Analysis, Transmission Electron Microscope (TEM), Tunable Resistive Pulse Sensing (TRPS), Mass Spectrometry, and other advanced technologies, ensuring reliable characterization across different research stages.
3. Exosomics Analysis Service
Our Exosomics Analysis Service combines Proteomics, Peptidomics, Metabolomics, Lipidomics and Modification Omics platform with label-free and labeled quantification, MRM/PRM-based targeted quantification and ultra-sensitive detection strategies to fully decode the molecular content and biological functions of exosomes, enabling biomarker discovery and mechanistic exploration.
4. Exosome Engineering Service
MtoZ Biolabs provides a complete suite of Exosome Engineering Services, including targeted surface modification, functional protein expression, cargo loading, molecular labeling, and delivery system construction. These services support customized engineering for disease-, tissue-, or cell-type targeting, facilitating efficient delivery of RNA, proteins, or small molecules for research and therapeutic development.
5. Exosome Manufacturing Service
We offer standardized Exosome Manufacturing Service, including large-scale production of stem cell-derived exosomes and evaluation of key quality attributes such as stability, purity, repeatability, specificity, safety, and production yield. The service supports the development of high-quality exosome products for downstream applications.
6. Extracellular Vesicle Related Research Service
Our EV research go beyond exosomes to include comprehensive analysis of various extracellular vesicles. This includes EV isolation, quantification, profiling, functional validation, engineering, and manufacturing to provide a complete framework for system-level EV studies and applications.
Analysis Workflow
Service Advantages
1. Broad Applicability
MtoZ Biolabs offers a diverse range of isolation protocols tailored to different sample types. Whether from animal, plant, or microbial origins, we can deliver high-quality exosome extraction and purification to support downstream research.
2. Multi-Omics Integration
Our platform supports transcriptomics, proteomics, metabolomics, and lipidomics, allowing for both single-omics and multi-omics integration to reveal regulatory networks and biological insights mediated by exosomes.
3. Transparent Pricing
MtoZ Biolabs adheres to a transparent pricing model. All services come with detailed quotes and modular service options, enabling flexible combination and cost management. We also support phased project execution to ensure research investment remains predictable and manageable.
4. Customizable Solutions
We tailor analysis strategies based on clients' research objectives, sample types, and budget. From separation methods to omics depth, we offer customizable Exosome Analysis Services, including marker-specific assays, species-specific adaptations, and functional validation extensions.
Applications
1. Liquid biopsy and early disease screening
2. Tumor biomarker discovery and therapeutic target identification
3. Functional studies of stem cell-derived exosomes
4. Mechanistic research on BBB crossing
5. RNA or protein delivery platform development
6. Exosome-based vaccine carrier design
7. Disease-specific exosome engineering
FAQs
Q: What is the typical turnaround time of Exosome Analysis Services?
A: Standard projects take approximately 3–6 weeks, depending on the selected modules, sample type, and quantity. We will provide a detailed timeline before project initiation and maintain regular communication during execution.
Sample Submission Suggestions
1. Recommended sample types: Cell culture supernatant (≥10 mL), serum/plasma (≥500 μL), urine (≥10 mL), cerebrospinal fluid, etc.
2. Other sample types: For low-volume or special samples, please consult our technical team for tailored recommendations.
3. Preprocessing: Avoid severe hemolysis, contamination, or multiple freeze-thaw cycles
4. Storage and shipping: Store at –80°C; ship on dry ice
5. Customer-extracted exosomes: Must meet purity and integrity standards; background information required
Deliverables
1. Complete analysis report
2. Characterization data and interpretation (graphs + summaries)
3. Raw omics data (e.g., Fastq, Raw MS, Excel)
4. Bioinformatics files (DE analysis, functional annotation, pathway enrichment)
5. Data visualizations (PCA, heatmaps, volcano plots, etc.)
Exosome research is rapidly transforming precision medicine, liquid biopsy, and regenerative therapy. With a robust analytical platform and a team of experienced scientists, MtoZ Biolabs provides comprehensive, efficient, and reliable Exosome Analysis Services to support your research from early-stage discovery to translational application.
Contact us today for a customized exosome analysis solution and move your research forward with clarity and confidence.
How to order?
