High-Throughput Glycan Screening Solution
High-Throughput Glycan Screening Solution is designed to provide rapid, sensitive, and comprehensive analysis of glycan composition, structural features, and modification patterns across diverse samples. Glycans play essential roles in immune regulation, signal transduction, pathogen recognition, and the stability of therapeutics, and even subtle structural changes can result in significant functional differences. With the fast-paced development of glycomics research and the biopharmaceutical industry, there is a growing demand for efficient, scalable, and reproducible analytical workflows that can meet the requirements of large-scale studies and complex research objectives.
Leveraging a multi-platform, multi-technology portfolio, MtoZ Biolabs develops integrated high-throughput glycan screening service framework that accommodates a wide range of sample types and analytical dimensions. Our High-Throughput Glycan Screening Solution covers the entire analytical spectrum from basic qualitative profiling to high-precision quantitative measurements, and from structural elucidation to structure–function correlation, providing research and industry clients with truly end-to-end analytical support.
Services at MtoZ Biolabs
MtoZ Biolabs delivers a full suite of High-Throughput Glycan Screening Solution utilizing a diverse set of advanced analytical platforms to address varying research goals and application contexts. Our offerings include:
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Sub-Service |
Brief Description |
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Automated LC-MS-Based High-Throughput Glycan Screening Solution |
Ideal for projects requiring high automation and large-scale batch processing, enabling rapid sample loading, data acquisition, and preliminary analysis with minimal manual intervention while ensuring consistency across runs. |
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Mass Spectrometry-Based High-Throughput Glycan Screening Solution |
Suitable for structurally diverse glycans that require high-resolution analysis, enabling simultaneous quantitation and structural characterization. This approach is widely applied in glycomics and metabolomics. |
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Designed for trace glycan detection and pharmaceutical quality control, offering exceptional sensitivity and resolution. It is particularly effective for glycans analyzed after fluorescent labeling derivatization. |
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Hydrophilic Interaction Chromatography-Based High-Throughput Glycan Screening Solution |
Provides high separation efficiency for highly polar glycans, making it ideal for screening complex biological matrices and multi-component glycan mixtures. |
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MALDI-TOF-MS-Based High-Throughput Glycan Screening Solution |
Recognized for rapid detection and high throughput, making it well suited for preliminary screening, large-scale comparisons, biomarker discovery, and cohort-based studies. |
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Excels at separating structurally similar glycans, enabling detailed isomer resolution and stereochemical analysis. |
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Provides stable, standardized quantitative glycan analysis, suitable for long-term quality monitoring and reference standard comparisons. |
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Enables deep structural elucidation and accurately determines glycan composition, linkages, branching patterns, and modification sites. This approach is ideal for complex glycan research and mechanism-based studies. |
Analysis Workflow
1. Sample Preparation and Pretreatment
Extract, purify, and concentrate samples according to their origin and the analytical objectives.
2. Glycan Release and Purification
Release glycans enzymatically or chemically, followed by purification via SPE, HILIC, or other approaches.
3. Separation and Detection
Perform chromatographic separation and mass spectrometric detection according to the selected analytical platform.
4. Data Acquisition and Processing
Collect high-resolution data and use specialized analytical software for peak identification, quantitation, and structural elucidation.
5. Result Delivery
Provide visualized analytical reports and detailed technical interpretations to support downstream research.
Why Choose MtoZ Biolabs?
✅ Multi-Platform Integration. Supports a broad range of mass spectrometry and chromatography combinations, ensuring unmatched analytical adaptability.
✅ High Throughput with Reproducibility. Optimized for batch processing while ensuring consistent and reliable results.
✅ Advanced Structural Analysis Capabilities. Enables detailed characterization of complex isomers and a variety of modification types.
✅ Tailored Solutions. Analytical workflows are customized according to sample type, complexity, and specific research goals.
✅ One-Time-Charge: Our pricing is transparent, no hidden fees or additional costs.
Sample Submission Suggestions
We accept a wide range of sample types, including biological specimens such as blood, urine, tissues, and cell culture supernatants, as well as food products, fermentation derivatives, and purified glycoproteins. Clients should clearly indicate the sample source and relevant details upon submission to facilitate suitability assessment. MtoZ Biolabs can provide comprehensive sample submission and preparation guidelines upon request.
Applications
● Disease Mechanism Research. Characterize glycan modification patterns linked to cancer, autoimmune diseases, and infectious diseases.
● Drug Quality Control. Evaluate glycosylation consistency in biopharmaceuticals to meet regulatory and submission requirements.
● Functional Food Development. Determine the types and levels of natural oligosaccharides and polysaccharides in food products.
● Environmental and Microbiology Studies. Analyze glycan features in environmental samples and microbial metabolic products.
Choosing the MtoZ Biolabs High-Throughput Glycan Screening Solution ensures efficient, accurate, and reproducible glycan profiling that supports the complete research continuum from fundamental studies to clinical translation. Contact us to receive a tailored technical solution and quotation.
FAQ
Q1: How does high-throughput glycan screening differ from conventional glycan analysis?
High-throughput screening focuses on the rapid processing of large sample sets while obtaining both structural and quantitative data, making it highly suitable for large-scale or cohort-based studies. Conventional analysis, in contrast, often emphasizes detailed characterization of a single or a small number of samples, with greater attention to complex structural features.
How to order?
