Pancreatic Cancer Exosome Research Service
- Isolated Exosomes: ≥200 μg total protein or ≥100 μL in PBS
- Plasma/Serum: ≥2 mL per sample
- Cell Culture Supernatants: ≥5 mL per sample
- Other Body Fluids: Please inquire for specific requirements
Pancreatic cancer is one of the most aggressive and lethal malignancies, characterized by late diagnosis, limited treatment options, and poor overall survival rates. Despite ongoing advances in molecular oncology and immunotherapy, the five-year survival rate remains dismally low, underscoring the urgent need for deeper mechanistic understanding and more effective diagnostic and therapeutic strategies.
Exosomes play multifaceted roles in pancreatic cancer (PC) progression. Depending on their cellular origin, exosomes can either enhance or suppress PC cell proliferation. The complex regulatory network remains to be fully defined. In terms of metastasis, tumor-derived exosomes facilitate extracellular matrix remodeling, activate stromal components, and promote angiogenesis, collectively driving cancer cell invasion. Moreover, exosomes contribute to chemoresistance by transferring resistance-associated molecules—including RNAs, proteins, and signaling mediators—from drug-resistant cells or the tumor microenvironment to sensitive PC cells.
Figure 1. Various Effects of Exosomes on Pancreatic Cancer Progression
Service at MtoZ Biolabs
To support researchers in uncovering the multifaceted roles of exosomes in pancreatic cancer, MtoZ Biolabs offers a comprehensive Pancreatic Cancer Exosome Research Service. MtoZ Biolabs' tailored services include:
💠Exosome Isolation and Purification
We offer high-efficiency isolation from blood, tissue, or cell culture using ultracentrifugation, size exclusion, affinity-based methods, and more.
Utilizing NTA, TEM, and Western blotting, we confirm particle size, morphology, and marker expression.
Our platform supports surface modification and cargo loading for functional studies and therapeutic applications.
💠Exosome Labeling and Tracking
We provide in vivo and in vitro tracking using fluorescent labeling, BLI, MRI, CT, and more.
💠Exosome Multi-Omics Analysis
Comprehensive profiling of exosomal proteins, lipids, metabolites, and RNAs using high-resolution LC-MS/MS and NGS platforms.
💠Exosomal Biogenesis and Identification
Our service supports researchers in dissecting the molecular mechanisms of exosome biogenesis and tracking key regulatory pathways.
💠Exosome Functional Analysis (In Vitro & In Vivo)
Functional assays assess the impact of exosomes on cell proliferation, invasion, immune modulation, and drug resistance using established models.
Analysis Workflow
Service Advantages
☑️Advanced Analysis Platform: MtoZ Biolabs established an advanced Pancreatic Cancer Exosome Research Service platform, guaranteeing reliable, fast, and highly accurate analysis service.
☑️Integrated Multi-Omics Capability: We combine proteomics, transcriptomics, lipidomics, and metabolomics to deliver a comprehensive understanding of pancreatic cancer–related exosomal biology.
☑️End-to-End Customization: From isolation and characterization to functional validation, all steps are tailored to your sample type, research goals, and specific pancreatic cancer subtype.
☑️Strict Quality Control & Confidentiality: All workflows follow standardized SOPs with validated reagents, ensuring data integrity, compliance, and full confidentiality of client projects.
Applications
MtoZ Biolabs' Pancreatic Cancer Exosome Research Service supports a wide range of research and translational objectives, including:
1️⃣Biomarker Discovery: Identification of exosomal RNA, protein, and lipid markers for early detection, prognosis, and monitoring of pancreatic cancer.
2️⃣Mechanistic Insights: Investigation of exosome-mediated mechanisms underlying tumor proliferation, immune evasion, angiogenesis, metastasis, and drug resistance.
3️⃣Therapeutic Target Identification: Analysis of exosomal components and their signaling pathways to uncover potential molecular targets for anti-cancer therapies.
4️⃣Liquid Biopsy Development: Characterization of circulating exosomes from patient samples to develop minimally invasive diagnostic assays.
5️⃣Exosome-Based Therapeutics: Evaluation of engineered or natural exosomes as delivery vehicles for drugs, siRNAs, or immunomodulatory agents in pancreatic cancer treatment.
Sample Submission Suggestions
We accept the following sample types:
Samples should be stored at -80°C and shipped on dry ice. Avoid repeated freeze–thaw cycles.
*Please consult us for tailored collection and storage protocols to maximize data quality.
Deliverables
1. Comprehensive experimental details (materials, instruments, and methods)
2. Raw data
3. Processed omics data files
4. Quality control reports (NTA, Western blot, TEM images)
5. Functional assay results
6. Bioinformatics analysis
7. Customized report based on project requirements
MtoZ Biolabs is committed to advancing pancreatic cancer research by providing comprehensive, high-quality exosome analysis services tailored to your scientific needs. Free project evaluation, welcome to learn more details!
Related Services
Exosome Isolation and Purification Service
Exosome Marker Analysis Service
Exosomes Identification Service
Exosomes Labeling and Tracking Service
How to order?
