Mass Spectrometry-Based Metabolomics Analysis Service
- Detailed experimental information including methods and conditions
- Raw data files
- Spectral and chromatographic outputs
- Data preprocessing and analysis results
- Bioinformatics analysis
- A tailored report based on project needs
Mass Spectrometry-Based Metabolomics Analysis Service is a comprehensive analytical solution designed to investigate the small molecules that shape biological function and phenotype. By utilizing advanced mass spectrometry platforms, this service enables the accurate detection, identification, and quantification of metabolites across a wide range of biological systems. MtoZ Biolabs provides a Mass Spectrometry-Based Metabolomics Analysis Service to help researchers gain deeper insights into metabolic processes. Our approach leverages the high sensitivity and resolution of mass spectrometry to capture both abundant and trace metabolites, offering a direct snapshot of physiological and pathological states.
The principle of mass spectrometry-based metabolomics lies in separating complex mixtures using chromatographic techniques, ionizing metabolites into charged species, and measuring their precise mass-to-charge ratios. Tandem MS and advanced bioinformatics workflows further allow structural elucidation and pathway mapping, ensuring that results are both accurate and biologically meaningful.
Alseekh, S. et al. Nat Methods. 2021.
Figure 1. Workflow for Mass Spectrometry-Based Metabolomics
Service at MtoZ Biolabs
MtoZ Biolabs offers a complete portfolio of metabolomics services to address diverse scientific needs.
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Comprehensive profiling of metabolites from tissues, biofluids, cells, microbial samples and other biological samples. |
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Broad, unbiased detection of metabolites to discover novel biomarkers and pathways. |
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Precise quantification of predefined metabolites linked to specific biological questions. |
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Balanced approach enabling both focused quantification and discovery-driven exploration. |
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Identification of metabolites and annotation of unknown compounds in complex mixtures. |
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Accurate measurement of metabolite concentrations to support rigorous statistical comparisons. |
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Approximate estimation of metabolite abundance ranges when absolute quantification is not feasible. |
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Tracing of metabolic pathways and fluxes using stable isotope-labeled precursors. |
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Determination of molecular frameworks, substructures, and stereochemistry of metabolites. |
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High-precision measurement of metabolite molecular weights for identification and verification. |
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Multi-stage fragmentation analysis to resolve complex molecular structures. |
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Characterization of molecular ion shape and conformation through ion mobility techniques. |
Service Advantages
✔️Comprehensive Detection
Capable of covering a wide spectrum of metabolites, from polar to nonpolar compounds, across various biological specimens.
✔️High Sensitivity and Accuracy
Advanced mass spectrometry platforms ensure detection of both trace and abundant metabolites with precise quantification.
✔️Flexible Analytical Modes
Supports untargeted discovery, targeted quantification, semi-targeted profiling, and isotopic labeling depending on project needs.
✔️One-Stop Workflow
From sample extraction to data analysis and interpretation, clients receive complete and integrated solutions.
✔️Robust Quality Control
Rigorous QC procedures guarantee reproducibility and reliability across different experiments and projects.
✔️Customizable Reporting
Deliverables are tailored to client goals, suitable for research publications, clinical studies, or regulatory submissions.
Sample Submission Suggestions
1. Sample Types
Microbial cultures, cell cultures, animal tissues, plant tissues, animal biofluids, and other biological samples.
2. Storage and Transport
Samples should be snap-frozen and stored at –80°C, shipped on dry ice, and protected from repeated freeze–thaw cycles.
3. Notes
Avoid detergents, salts, preservatives, or other additives that may interfere with mass spectrometry detection.
Clients are encouraged to contact MtoZ Biolabs before sample preparation to receive tailored instructions for their specific project.
Deliverables
For more information about our Mass Spectrometry-Based Metabolomics Analysis Service, please contact us. Our technical specialists are available to provide a free business assessment.
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How to order?
