Metabolites Structural Elucidation Service
- Samples should be stored at -80℃ and shipped with dry ice.
- Avoid repeated cycles of freezing and thawing.
- Comprehensive Experimental Details
- Materials, Instruments, and Methods
- Total Ion Chromatogram & Quality Control Assessment (project-dependent)
- Data Analysis, Preprocessing, and Estimation (project-dependent)
- Bioinformatics Analysis
- Raw Data Files
MtoZ Biolabs provides a professional Metabolites Structural Elucidation Service designed to deliver high-confidence identification and characterization of metabolites across a wide range of biological and industrial contexts. By integrating advanced mass spectrometry and complementary analytical platforms with robust data interpretation, our service helps researchers uncover the precise structures of metabolites and their variants.
Metabolites form the chemical foundation of cellular processes. They include primary metabolites such as amino acids, nucleotides, fatty acids, and sugars, as well as secondary metabolites like alkaloids, terpenoids, phenolics, and flavonoids. Understanding metabolite structures is essential because structure dictates function. A single change in the arrangement of functional groups, stereochemistry, or conjugation can significantly alter the biological activity, toxicity, stability, and pharmacokinetics of a compound.
Metabolites' structural elucidation plays a critical role in fields such as drug discovery, biomarker identification, nutrition science, agriculture, and environmental studies. In pharmaceuticals, identifying unknown metabolites of drug candidates is essential for safety evaluation and regulatory submission. In systems biology, structural characterization of metabolites enables the mapping of metabolic pathways. In food science, structural analysis of bioactive metabolites helps validate nutritional benefits. Across all these disciplines, reliable structural elucidation ensures that metabolite function is understood at the molecular level.
Service at MtoZ Biolabs
MtoZ Biolabs offers a comprehensive structural elucidation solution tailored to metabolite analysis. Our services combine advanced mass spectrometry with chromatographic separation and complementary structural techniques to achieve high-confidence metabolite characterization. We apply optimized ionization methods and high-resolution analyzers to determine exact masses, isotopic distributions, and fragmentation profiles. By integrating tandem MS with ion mobility spectrometry and complementary NMR validation when necessary, we deliver detailed insights into molecular frameworks, substructures, and stereochemistry.
Our workflows are adaptable to a broad spectrum of metabolite classes, including small polar molecules, lipids, sugars, alkaloids, and complex natural products. Whether the goal is identifying unknown metabolites in untargeted studies or verifying known metabolites for regulatory submission, our team provides robust and reproducible data. Clients benefit from customized experimental designs, precise data interpretation, and reports that are suitable for publication and regulatory documentation.
Reher, R. et al. Nat Commun. 2022.
Figure 1. Structure Elucidation Workflow Based on NMR and MS/MS Data
Service Advantages
☑️High precision in molecular formula determination using high-resolution mass spectrometry
☑️Capability to analyze a wide range of metabolite classes, including small polar molecules, lipids, sugars, alkaloids, and natural products
☑️Customizable workflows that adapt to both untargeted discovery and targeted verification studies
☑️Strict quality control measures that ensure reproducibility and regulatory-ready results
☑️Professional scientific support from project planning through to data interpretation and reporting
Sample Submission Suggestions
Note: If you have special sample types or require additional guidance, please contact us for personalized support before sample preparation.
Deliverables
Our Metabolites Structural Elucidation Service is designed to provide more rapid, high-throughput, and cost-effective analysis, with exceptional data quality and minimal sample consumption. Free project evaluation, welcome to learn more details.
How to order?
