Mass Spectrometry-Based Service
Mass spectrometry (MS) is a powerful analytical technology widely applied in proteomics, metabolomics, and biopharmaceutical characterization. By measuring the mass-to-charge ratio (m/z) of ions, MS enables the identification of unknown compounds, the quantification of known targets, and the elucidation of molecular structures or chemical properties. These capabilities make it an indispensable tool in modern life sciences research.
MtoZ Biolabs specializes in proteomics and provides a comprehensive Mass Spectrometry-Based Service platform. By integrating advanced instrumentation with a skilled scientific team, we deliver reliable, reproducible, and publication-ready results, from experimental design to data interpretation.
Services at MtoZ Biolabs
A typical mass spectrometry system consists of an ion source, a mass analyzer, and an ion detector. In protein research, commonly used ionization techniques include electrospray ionization (ESI) and matrix-assisted laser desorption/ionization (MALDI). ESI is suitable for generating multiply charged ions for detailed fragmentation analysis, while MALDI offers rapid analysis with relatively low sample requirements. Based on our MS platform, MtoZ Biolabs provides a wide range of services, including but not limited to:
The specific services we can provide include:
1. Proteomics Analysis Service
2. Protein Identification Service
4. Protein Mass Spectrometry Sequencing Service
5. PTM Mass Spectrometry Analysis Service
6. Peptidomics Analysis Service
7. Biopharmaceutical Research Services
8. Metabolomics Analysis Service
9. Lipidomics Analysis Service
10. Preclinical Drug Development
11. Biomarker Discovery Service
Experimental Instruments
Thermo Scientific™ Orbitrap Fusion™ Lumos™
Thermo Scientific™ Q Exactive™ HF
Quadrupole Time-of-Flight Mass Spectrometer
Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometer
Analysis Workflow
Service Advantages
1. Cutting-edge instrumentation: High-resolution and high-sensitivity MS systems guarantee data quality and stability.
2. Standardized workflows: Rigorous protocols ensure reproducibility from sample handling to final reporting.
3. Versatile analytical capabilities: Comprehensive support for identification, quantification, structural analysis, modification profiling, and interaction mapping.
4. Expert team support: Collaboration between mass spectrometry specialists and bioinformatics experts ensures scientifically sound outcomes.
5. Customized solutions: Tailored strategies based on sample type and research objectives.
Sample Submission Suggestions
1. Proteins/peptides: ≥1 µg/µL, total ≥50 µg; avoid high salt, glycerol, or SDS; ship frozen at -80 °C.
2. Cells/tissues: ≥1×106 cells or ≥50 mg tissue, homogenized and frozen.
3. Small molecules/metabolites: ≥100 µL liquid or ≥5 mg solid; use LC-MS-compatible solvents (e.g., methanol, acetonitrile); avoid strong acids or bases.
4. Documentation: Provide complete information on sample name, concentration, buffer system, storage conditions, as well as experimental background and objectives to optimize the analytical plan.
Deliverables
1. Raw MS data files (RAW, mzML, or mzXML formats)
2. TIC and QC chromatograms
3. Method parameter files (LC gradients, ionization and acquisition settings)
4. Database search results: peptide/protein lists, modification sites, confidence scores
5. Quantitative reports (if applicable): relative or absolute quantification with statistical analysis
6. Bioinformatics outputs: functional annotation, pathway enrichment, interaction networks
7. Final comprehensive report with objectives, methodology, result interpretation, and visual figures
By combining advanced mass spectrometry platforms with a complete service workflow, MtoZ Biolabs is committed to providing rigorous, reproducible, and publication-ready proteomics solutions. Whether your project involves protein identification, structural modification analysis, biomarker discovery, or quantitative studies, our team can help advance your research to the next level.
Contact us today to receive a customized service plan tailored to your project and submission requirements.
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