Untargeted Metabolites Profiling Service
MtoZ Biolabs offers a comprehensive Untargeted Metabolites Profiling Service designed to capture broad and unbiased profiles of metabolites, enabling researchers to gain novel insights into metabolic dynamics across diverse biological systems.
Untargeted metabolomics is a widely applied research approach that uses advanced technologies such as LC-MS, GC-MS, and NMR to detect small-molecule metabolites without prior assumptions. By analyzing cells, tissues, organs, or entire organisms before and after biological or environmental perturbations, this method reveals the dynamic changes of endogenous metabolites. Differential metabolites are identified through rigorous bioinformatics pipelines and further mapped to metabolic pathways to uncover their physiological and pathological significance. Comparing profiles between experimental and control groups provides a valuable foundation for biomarker discovery, understanding disease mechanisms, and elucidating drug actions.
Service at MtoZ Biolabs
MtoZ Biolabs provides a full-process Untargeted Metabolites Profiling Service that allows researchers to focus on their scientific questions while we handle every stage of the workflow. Clients only need to prepare and deliver suitable biological samples, and our team manages the rest, from extraction and instrumental analysis to data processing and interpretation.
We employ LC-MS, GC-MS, and NMR platforms to maximize metabolite coverage and sensitivity. After sample processing, thousands of metabolite features are detected, annotated, and statistically evaluated. Differential metabolites are mapped to biochemical pathways through advanced bioinformatics pipelines, offering clear insights into metabolic mechanisms.
Analysis Workflow
Zeki, Ö. C. et al. J. Pharm. Biomed, 2020.
Figure 1. Untargeted Metabolomics Analysis Workflow
Why Choose MtoZ Biolabs?
✔️Extensive expertise in metabolomics research with proven experience in complex projects
✔️Advanced analytical platforms ensuring broad metabolite coverage and reproducible results
✔️One-stop service model where clients only provide samples and we deliver complete analysis and interpretation
✔️Strong bioinformatics capabilities for reliable metabolite annotation and pathway integration
✔️Tailored solutions that adapt to the unique needs of clinical, pharmaceutical, agricultural, nutritional, and environmental studies
✔️Commitment to high data quality, transparent communication, and timely delivery
Applications
1. Biomarker Discovery: Supports the identification of novel diagnostic or prognostic biomarkers by revealing differential metabolites between disease and control groups.
2. Disease Mechanism Research: Provides pathway-level insights into physiological and pathological changes for better understanding of disease development.
3. Drug Development: Helps assess therapeutic efficacy and detect off-target metabolic effects during preclinical and clinical studies.
4. Nutrition and Food Science: Enables the evaluation of dietary interventions and detection of bioactive compounds influencing health outcomes.
5. Agricultural and Plant Studies: Assists in profiling plant metabolites to investigate stress responses, crop quality, and yield.
6. Environmental Research: Facilitates the assessment of pollutant exposure and metabolic adaptations in ecosystems.
Sample Submission Suggestions
1. Sample Types
Microbial cultures, cell cultures, animal tissues, plant tissues, animal biofluids, and other biological samples.
2. Storage and Transport
Samples should be snap-frozen and stored at –80°C, shipped on dry ice, and protected from repeated freeze–thaw cycles.
3. Notes
Avoid detergents, salts, preservatives, or other additives that may interfere with mass spectrometry detection.
Clients are encouraged to contact MtoZ Biolabs before sample preparation to receive tailored instructions for their specific project.
Deliverables
1. Detailed experimental information including methods and conditions
2. Raw data files
3. Spectral and chromatographic outputs
4. Data preprocessing and analysis results
5. Bioinformatics analysis
6. A tailored report based on project needs
MtoZ Biolabs' Untargeted Metabolites Profiling Service provides a global perspective on metabolism, enabling the discovery of new biomarkers, clarification of disease mechanisms, and monitoring of environmental or industrial processes. Contact us today to discuss your project and request a customized proposal!
Related Services
How to order?
