LC-MS Peptidomics Service

MtoZ Biolabs provides LC-MS peptidomics service using high-resolution liquid chromatography mass spectrometry platforms and multi-dimensional data analysis strategies to deliver comprehensive peptide profiling, sequence identification, quantitative analysis, and multi-omics integration for clients in research, pharmaceutical, and biotechnology fields. This service helps users accurately characterize the composition, dynamic changes, and biological significance of endogenous peptides, supporting disease research, target discovery, drug mechanism elucidation, and biomarker development.

 

LC-MS Peptidomics Service at MtoZ Biolabs

MtoZ Biolabs offers a comprehensive analytical system covering peptide sample preparation, sequence identification, and functional interpretation, supporting research needs in basic science, translational studies, oral health research, inflammation mechanisms, and drug development.

 

Peptide Sample Preparation Service	Peptide Purification Service	Qualitative Peptidomics Service	Quantitative Peptidomics Service
Peptide Sequencing Services	Peptide-Biomolecule Interaction Identification Service	Integrated Immunopeptidomics Analysis Service	Peptide Related Impurity Analysis Service
Peptidomics and Multi-omics Analysis Service	Peptide Identification Service	Peptide Structure Determination Service	Peptidomics-Based Analysis Service

 

Workflow of LC-MS Peptidomics Service

 



Hellinger, R. et al. Nat Rev Methods Primers. 2023.

Figure 1. Peptidomics Analysis Workflows

Why Choose MtoZ Biolabs

1. Professional Team

The analytical team specializes in peptidomics, noninvasive fluid studies, immunopeptidomics, and functional peptide analysis. They are familiar with peptide characteristics across different sample types and can provide effective data interpretation and technical recommendations.

 

2. Advanced Platform

High-resolution LC-MS/MS systems and stable automated sample processing workflows combined with multi-dimensional data analysis algorithms ensure high sensitivity, accurate identification, and reliable quantitative performance.

 

3. Customized Services

Qualitative, quantitative, immunopeptidomics, and degradation or bioactive peptide studies can be customized based on project needs, supporting basic research, disease mechanism studies, drug development, and multi-omics integration.

 

4. Full Laboratory Support

Offers one-stop solutions from preparation and separation to detection.

 

5. One-Time Charge

Our pricing is transparent with no hidden fees or additional costs.

 

Applications of LC-MS Peptidomics Service

· Endogenous peptide studies related to disease, including inflammation, cancer, metabolic disorders, and neurodegenerative diseases

· Noninvasive biofluid studies such as saliva, oral multi-omics, and urine

· Drug mechanism of action analysis

· Biomarker discovery and verification

· Functional studies of degradation fragments and bioactive peptides

· Immune peptide presentation research

· Microbial peptide identification

· Proteolytic pattern and enzyme activity analysis

 

Deliverables

1. Sample processing and workflow descriptions

2. LC-MS raw data files

3. Identified peptide lists and sequence information

4. Quantitative result tables and statistical analysis

5. Modification information such as oxidation or truncation

6. Complete PDF report and visualized figures

 

FAQs

Q1: What types of samples are suitable?

· Plasma, urine, saliva, and other biofluids

· Cellular and tissue samples

· Synthetic peptides or purified peptide products

 

Q2: What is the service's general workflow?

 

 

Q3: What data formats are provided?

MtoZ Biolabs provides multiple standardized data formats to support downstream analysis and visualization, including:

· Raw mass spectrometry data files (RAW)

· Processed peptide identification and quantification tables in CSV or Excel format

· A complete PDF report containing workflow details, quality control, and major findings

· Figures and visual outputs in TIFF or PNG format, including chromatograms, spectra, and statistical plots

 

Customized formats or specialized data structures can be provided according to research or publication requirements.

 

Q4: How should I prepare my samples?

To ensure accurate, stable, and reproducible peptidomics results, please follow these preparation guidelines:

1. Sample Type: A variety of sample types are accepted, including plasma, serum, saliva, urine, tissue homogenates, cell lysates, and purified peptides.

2. Sample Quality: Samples should be free of particulates, high salt, strong acidic or basic substances, metal ions, or detergents to ensure optimal chromatographic separation and ionization.

3. Volume or Weight Requirement: Provide at least 200 μL of liquid sample or 20 mg of tissue. Additional material is recommended for replicates.

4. Storage and Shipping: Store samples at −80 °C, ship them on dry ice, and use sealed, leak-proof packaging to maintain sample stability.

5. Sample Information Documentation: Provide sample origin, preparation method, buffer composition, and relevant background information to support optimal method setup.

 

For more information, please refer to Sample Submission Guidelines for Proteomics and Sample Submission Guidelines for Metabolomics.

 

If you are unsure about your sample preparation, our technical team can provide personalized pre-analysis consultation and a sample submission guide to help you optimize preparation and shipping conditions.

 

Start Your Project with MtoZ Biolabs

Feel free to contact us. We will develop an appropriate analytical plan based on your research needs and support the successful progress of your project.