Peptide Service
- Peptide–antibody/protein/DNA/lipid interaction profiling
- Comprehensive peptide binding partner identification
- C-/N-terminal peptide sequencing
- Peptide purity and integrity analysis
- Glycopeptide/lipid-peptide structure recognition
- Signature peptide identification and qualitative profiling
- Peptide expression profiling
- Differential peptide abundance analysis
- Targeted peptide quantification using PRM/MRM
- Isotopic labeling-based quantification
- HLA-associated peptide identification
- Epitope mapping and neoantigen analysis
- MHC binding prediction
- Immune response profiling and vaccine design support
- Peptidomics in various tissue types (e.g., tumor, neural, microbial, plant)
- Disease-specific peptide profiling
- Cross-species peptidomics (human, mouse, bovine, porcine, etc.)
- Integration with histology, transcriptomics, and metabolomics
- Biological fluids: serum, plasma, cerebrospinal fluid, urine
- Tissue samples: fresh, frozen, or FFPE tissues from human or animal sources
- Cultured cells: cell pellets or lysates from adherent or suspension cultures
- Supernatants: conditioned media or extracellular vesicle-enriched fractions
- Synthetic or purified peptides: lyophilized or in solution
- Enzymatic digests: protein or antibody digests (e.g., trypsin, Glu-C)
Peptides, serving as a vital bridge between proteins and small molecules, play crucial roles in signaling, immune regulation, and cellular communication. With the rise of multi-omics technologies and advanced analytical platforms, peptide research has evolved far beyond basic sequence identification to include post-translational modification analysis, structural elucidation, functional mapping, and therapeutic targeting.
MtoZ Biolabs offers an integrated peptidomics platform powered by cutting-edge mass spectrometry, deep informatics, and robust reference databases. Our end-to-end solutions span peptide discovery, structural and functional annotation, mechanism of action studies, and translational applications, empowering researchers across academia, biotechnology, and pharmaceuticals to fully characterize and harness the potential of peptides.
Service at MtoZ Biolabs
To address a wide range of research and development needs, MtoZ Biolabs provides a modular peptidomics service portfolio divided into five major categories:
1. Peptide-Molecule Interactions
Focused on investigating the molecular interactions between peptides and biological targets such as antibodies, proteins, DNA, or lipids, supporting target validation and mechanism studies.
2. Qualitative Peptidomics
Dedicated to the identification and structural characterization of peptides, including terminal sequencing, purity evaluation, and PTM profiling.
3. Quantitative Peptidomics
Supporting both relative and absolute quantification via a range of labeling and label-free methods such as TMT, iTRAQ, PRM, MRM, and SILAC.
4. Immunopeptidomics
Designed for immunology and vaccine research, this service focuses on antigenic peptide discovery, HLA-binding analysis, and immune escape mechanism exploration.
5. Tissue-Based Peptidomics and Integrated Multi-Omics
Combining peptidomics with tissue proteomics, metabolomics, and spatial biology to reveal tissue-specific and spatiotemporal distribution of peptides under physiological or pathological conditions.
Why Choose MtoZ Biolabs?
✅Dedicated Peptidomics Platform：Equipped with Orbitrap, Q-TOF, and triple quadrupole systems to meet both discovery and targeted quantification needs.
✅Expert Scientific Team: Our multidisciplinary team includes specialists in proteomics, bioinformatics, immunology, and structural biology.
✅Integrated Multi-Omics Insight：Peptide data contextualized with proteomics, glycomics, and spatial transcriptomics for biological insight.
✅One-Time-Charge: Our pricing is transparent, no hidden fees or additional costs.
✅High-Data-Quality: Deep data coverage with strict data quality control. AI-powered bioinformatics platform integrates all peptides analysis data, providing clients with a comprehensive data report.
Applications
Drug and Vaccine Development: Target identification, mechanism validation, peptide-based therapeutics, and vaccine design.
Biomarker Discovery: Differential peptide expression profiling for disease diagnosis, prognosis, or therapeutic response prediction.
Food and Cosmetics Research: Characterization of functional and bioactive peptides in food or cosmetic formulations.
Functional Studies: Analysis of peptides involved in signal transduction, metabolism, and regulatory networks.
Synthetic Biology: Engineering novel peptide scaffolds with optimized activity and stability.
Sample Submission Guidelines
MtoZ Biolabs accepts a wide range of biological and synthetic sample types for peptidomics analysis, including but not limited to:
To ensure optimal results, we recommend:
1. A minimum peptide/protein amount of 50–200 µg for standard analyses (label-free or labeling-based), depending on the project scope
2. Sample concentration ≥1 µg/µL for LC-MS/MS-based workflows
3. Avoidance of detergents (e.g., SDS) and high salt concentrations during sample preparation
4. Providing detailed sample background information (species, treatment, expected modifications, etc.)
Deliverables
Raw mass spectrometry data files
Peptide identification results (FASTA/CSV)
PTM and structural annotation reports
Quantitative analysis and differential expression data
Custom visualizations and technical reports
How to order?
