Peptidomics-Based Food Fermentation Research Service

Fermentation is one of the oldest and most widely used food processing techniques, enhancing food preservation, flavor, texture, and nutritional value. During fermentation, microorganisms such as bacteria, yeasts, and molds break down complex organic compounds into simpler compounds, producing bioactive peptides, organic acids, alcohols, and gases. These biochemical transformations are critical for the quality and safety of fermented foods.

Traditionally, the study of fermentation has focused on monitoring microbial growth, metabolic byproducts, and physical changes. However, understanding the intricate biochemical processes at the molecular level, particularly those involving peptides, has gained increasing attention. Peptides generated during fermentation can have significant physiological effects, including antimicrobial, antioxidant, antihypertensive, and immunomodulatory properties. Peptidomics, the large-scale study of peptides in biological systems, provides a powerful tool for understanding these fermentation-derived bioactive peptides. By profiling the peptides produced during fermentation, researchers can gain insights into microbial activity, fermentation kinetics, and the functional benefits of fermented foods.

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Peres, Fabbri, L. et al. Foods. 2024.

Figure 1. Bioactive Peptides from Fermented Foods

Service at MtoZ Biolabs

MtoZ Biolabs offers a Peptidomics-Based Food Fermentation Research Service that combines advanced mass spectrometry, in-depth peptide analysis, and bioinformatics to help researchers and food developers monitor, optimize, and enhance fermentation processes. Our service enables the identification, characterization, and functional analysis of fermentation-derived peptides, providing valuable information to improve food quality, safety, and health benefits.

We offer the following key analyses:

💠Peptide Identification

Using high-resolution LC-MS/MS, we identify a wide range of endogenous and fermentation-derived peptides. This includes both known and novel sequences, enabling detailed mapping of proteolytic activity and fermentation progress.

💠Accurate Peptide Quantification

We quantify peptides across different fermentation stages using label-free or isotopic approaches. This allows monitoring of peptide abundance over time, supporting kinetic studies and process optimization.

💠Peptide Structure and Sequence Analysis

Our platform provides detailed sequence information, including amino acid composition, post-translational modifications, and cleavage site mapping. This enables characterization of the structure–function relationship of key peptides.

💠Peptide Interaction and Target Prediction

Using molecular docking and predictive bioinformatics tools, we analyze potential interactions between bioactive peptides and their biological targets, such as enzymes, receptors, or microbial proteins.

Using these analyses, we can help researchers:

1️⃣Monitor Peptide Changes During Fermentation

Track the dynamic shifts in peptide profiles throughout the fermentation process to understand microbial activity and product development.

2️⃣Detect Functional Peptides in Food

Identify bioactive peptides with specific health benefits, such as antioxidant, antimicrobial, and antihypertensive properties, in fermented food products.

3️⃣Analyze Protein Hydrolysis Patterns

Examine the patterns of protein degradation and proteolytic activity during fermentation, providing insights into enzyme actions and their impact on food quality.

4️⃣Optimize Fermentation Processes

Use peptide profiling to optimize fermentation conditions, improve product consistency, and enhance the functional properties of the final product.

5️⃣Identify Allergens and Toxins in Fermentation

Detect potential allergens and toxins produced during fermentation, ensuring food safety and regulatory compliance.

Analysis Workflow

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Service Advantages

☑️Advanced Analysis Platform: MtoZ Biolabs established an advanced Peptidomics-Based Food Fermentation Research Service platform, guaranteeing reliable, fast, and highly accurate analysis service.

☑️Comprehensive Service Offering: From peptide profiling to bioactivity screening and bioinformatics analysis, we provide a complete solution for your fermentation research needs.

☑️Customizable Research Solutions: Our services are tailored to meet specific fermentation processes, food types, and research objectives, providing flexible and scalable solutions.

☑️Expert Team: Our team of scientists and bioinformaticians brings extensive expertise in peptidomics and food science, ensuring high-quality results and reliable insights.