Cysteinylation Proteomics Service
Cysteinylation refers to the covalent attachment of a cysteine residue on a protein to a cysteine-containing molecule, such as glutathione (GSH), cysteine, or other reactive thiol-based molecules. This modification typically occurs in response to oxidative stress, cellular signaling, and metabolic changes. The addition of cysteine-containing molecules like glutathione can protect proteins from oxidative damage, stabilize protein structure, or regulate enzyme activity. Cysteinylation is often dynamic and reversible, allowing it to act as a signaling mechanism within the cell. It is involved in redox regulation, especially in the protection against oxidative damage and maintaining cellular homeostasis. Importantly, cysteinylation is implicated in immune response regulation, protein localization, and transcriptional control.
Service at MtoZ Biolabs
MtoZ Biolabs offers a comprehensive Cysteinylation Proteomics Service that enables researchers to identify, quantify, and functionally annotate cysteinylated peptides across a wide range of biological samples. Our integrated workflow ensures accurate detection of cysteinylation sites and the associated changes in protein function or signaling pathways, helping researchers uncover novel insights into cellular processes and disease mechanisms. We leverage the power of advanced LC-MS/MS systems to deliver high-resolution, high-sensitivity analysis of cysteinylation modifications. Our custom-designed enrichment techniques, combined with extensive bioinformatics support, provide a complete solution for cysteinylation studies, from sample preparation to data interpretation. In addition to Cysteinylation Proteomics, we also offer specialized services for other post-translational modifications, including phosphorylation, glycosylation, acetylation, and more.
Figure 1. Workflow for Cysteinylation Proteomics Service
Service Advantages
1. One-Stop Service
From sample preparation and analysis to bioinformatics interpretation, we offer a fully integrated solution to study cysteinylation and its biological impacts.
2. Flexible and Customizable
Our tailored workflows are adaptable to your experimental needs, whether you're studying basic biology, disease mechanisms, or drug targets.
3. High-Quality Results
We provide detailed, publication-ready reports that include raw data, peptide identification, quantification, and functional analysis.
4. One-Time-Charge
Our pricing is transparent, no hidden fees or additional costs.
Sample Submission Suggestions
Storage and Shipping: Samples should be stored at -80℃ and shipped with dry ice.
*Note: If you have specific requirements or need guidance on sample preparation, please do not hesitate to contact us.
Deliverables
1. Comprehensive Experimental Details
2. Materials, Instruments, and Methods
3. Total Ion Chromatogram & Quality Control Assessment (project-dependent)
4. Data Analysis, Preprocessing, and Estimation (project-dependent)
5. Bioinformatics Analysis
6. Raw Data Files
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