Resources

Proteomics Databases



Metabolomics Databases

• • Advanced LC-MS Method for DON (Vomitoxin) Detection in Food Products

  In the domain of food safety, the detection of deoxynivalenol (DON, commonly known as vomitoxin) remains a significant challenge. Produced by specific fungal species, this mycotoxin is frequently detected in grains and flour and can pose a wide range of health risks. With increasing public and industry concern regarding food safety, the accurate detection of DON has become a central focus for both regulatory agencies and food manufacturers. The LC-MS (liquid chromatography–mass spectrometry) platform ......

• • What Is SWATH Mass Spectrometry?

  With the rapid advancement of proteomics, mass spectrometry has become a central tool for uncovering the molecular mechanisms underlying biological processes. Mass spectrometry techniques have continuously evolved—from early Data-Dependent Acquisition (DDA) methods to more recent Data-Independent Acquisition (DIA) strategies—enabling significant improvements in the depth, accuracy, and reproducibility of proteomic data. Within the DIA framework, SWATH-MS (Sequential Window Acquisition of All Theoretical....

• • Quantitative Analysis of SWATH Proteomics Using OpenSWATH: A Complete Workflow Overview

  SWATH-MS (Sequential Window Acquisition of All Theoretical Mass Spectra) is a mass spectrometry technique based on Data-Independent Acquisition (DIA), and has gained widespread adoption in proteomics research in recent years. Owing to its excellent reproducibility, high throughput, and comprehensive proteome coverage, it has become a preferred approach for large-scale quantitative analysis. Among the available tools for processing DIA data, OpenSWATH stands out as one of the most widely used, offering an...

• • Applications and Breakthroughs of SWATH Proteomics in Agricultural Research

  In the era of precision and intelligent agriculture, elucidating the molecular mechanisms within crops and related organisms has become central to advancing crop breeding, improving disease management, and enhancing the quality of agricultural products. In recent years, SWATH (Sequential Window Acquisition of All Theoretical Mass Spectra) proteomics, a technique based on the Data-Independent Acquisition (DIA) approach, has emerged as a powerful analytical tool in agricultural research due to its .......

• • SWATH-MS vs DDA-MS: Which Technique Is Suitable for Your Research?

  In proteomics research, selecting an appropriate mass spectrometry acquisition method is crucial for obtaining high-quality data. Among the most prevalent approaches are SWATH-MS (Sequential Window Acquisition of all Theoretical fragment ion spectra) and DDA-MS (Data-Dependent Acquisition), each offering distinct advantages. A clear understanding of their underlying principles, application contexts, and technical limitations can guide researchers in developing sound experimental strategies. What Is DDA.....

• • SWATH-MS Enables Plant Proteomics Research: From Experiment to Data Analysis

  Plants, as complex and functionally diverse biological systems, display highly dynamic molecular regulatory mechanisms in response to environmental stress and in controlling their growth and development. To gain a deeper understanding of the fundamental processes underlying plant life, proteomics has emerged as a vital research tool, complementing genomics and transcriptomics. With advances in mass spectrometry, SWATH-MS (Sequential Window Acquisition of All Theoretical Fragment Ion Mass Spectra) is .......

• • Applications and Strategies of SWATH-MS-Based Proteomics in Clinical Research

  In contemporary clinical research, elucidating the molecular mechanisms of diseases, identifying early diagnostic biomarkers, and guiding personalized therapeutic strategies are recognized as core scientific challenges. As a pivotal tool linking gene expression to phenotypic variation, proteomics has been extensively employed across disciplines such as oncology, immunology, and neuroscience. In recent years, SWATH-MS (Sequential Window Acquisition of All Theoretical Fragment Ion Mass Spectra), a data.......

• • Label-Free Quantitative Proteomics Service Based on SWATH Technology

  With the advancement of proteomics research, label-free quantification techniques have garnered significant attention in fields such as disease mechanism elucidation, biomarker discovery, and drug development, owing to their high throughput and elimination of complex sample pretreatment. Among these, SWATH (Sequential Windowed Acquisition of All Theoretical Fragment Ion Spectra), a Data-Independent Acquisition (DIA) strategy, has emerged as a core methodology in label-free quantitative proteomics. It.......

• • High-throughput SWATH-MS Quantitative Proteomics for Biomarker Discovery

  Biomarkers are essential for early disease screening, subtype classification, personalized therapy, and treatment monitoring. As clinical research becomes increasingly precise, the technical demands for biomarker discovery have risen, particularly in the accurate detection of low-abundance proteins and achieving cross-batch data consistency. Mass spectrometry remains a cornerstone of proteomics research. However, the Data-Dependent Acquisition (DDA) approach, due to its stochastic sampling strategy, is.....

• • What Is DIA and SWATH? Understanding Data-Independent Acquisition in Proteomics?

  Mass spectrometry is a core technology in modern proteomics research. The choice of acquisition strategy critically influences data coverage, reproducibility, and quantitative accuracy. In recent years, Data-Independent Acquisition (DIA) has rapidly gained prominence and is increasingly considered a mainstream alternative to Data-Dependent Acquisition (DDA). Within the DIA framework, the most widely recognized implementation is SWATH-MS (Sequential Window Acquisition of All Theoretical Fragment Ion ........