Resources

Proteomics Databases



Metabolomics Databases

• • Proximity Proteomics

  Proximity proteomics is an advanced research strategy leveraging high-resolution mass spectrometry to investigate the spatial organization and functional dynamics of proteins within cellular environments. Unlike conventional proteomics, which primarily examines global protein expression and modifications, proximity proteomics focuses on the immediate molecular neighborhood and interaction networks of specific proteins with high spatial precision. By precisely labeling target proteins and their proxima......

• • LC-MS Protein Analysis

  LC-MS protein analysis is a powerful bioanalytical technique widely used to characterize complex protein mixtures. By integrating liquid chromatography (LC) and mass spectrometry (MS), LC-MS combines protein separation with molecular weight and structural characterization. In LC, proteins are fractionated into distinct components based on their physical and chemical properties, while MS identifies and analyzes these components with high precision. This technique has become indispensable in biomedical ......

• • Target Validation in Drug Discovery

  Target validation in drug discovery is a fundamental step in the drug development process. Its primary objective is to confirm whether specific molecules or proteins are involved in the onset and progression of diseases, and whether they can be targeted for effective drug intervention. During the early stages of drug discovery, target validation in drug discovery lays the foundation for the entire drug development pipeline, ensuring that the research direction is correct and has the potential for clin......

• • Epitope Mapping Services

  Epitope mapping services systematically identify and analyze specific regions of antigens or pathogens to locate critical immune response sites, known as epitopes. These services rely on the specificity of antigen-antibody interactions, where the immune system detects epitopes-typically short peptide sequences on antigens-and initiates immune responses. Advances in high-resolution mass spectrometry technology have significantly enhanced the precision and accuracy of epitope mapping services, enabling ......

• • Fmoc Solid Phase Peptide Synthesis

  Fmoc solid-phase peptide synthesis is a widely employed technique for the assembly of peptides. Unlike traditional liquid-phase synthesis, this method involves the stepwise attachment of amino acid monomers onto a solid-phase resin through a series of chemical reactions, ultimately constructing the desired peptide chain. The fundamental aspect of Fmoc solid-phase peptide synthesis lies in the application of the Fmoc group, a functional moiety that provides temporary protection to the amino group of am......

• • Amino Acid Quantification

  Amino acid quantification involves accurately measuring the types and concentrations of amino acids in a sample using precise analytical techniques. Amino acids are the fundamental building blocks of proteins and are involved in numerous physiological processes, including cellular metabolism, signal transduction, and immune responses. The composition and relative abundance of amino acids in the body play a vital role in maintaining health and preventing diseases. This analysis has broad applications a......

• • Single-Cell Genome Sequencing

  Single-cell genome sequencing is a technique that deciphers genomic information at the single-cell level, enabling precise identification of genomic variations, structural changes, and genetic diversity. This technology offers unparalleled resolution for investigating cellular heterogeneity, elucidating disease molecular mechanisms, and tracing cell evolutionary trajectories. A defining feature of this technology is its ability to provide high-resolution analysis of rare and complex cell populations. ......

• • Fmoc Peptide Synthesis

  Fmoc peptide synthesis is a widely used chemical method for synthesizing polypeptide chains, with applications spanning biochemistry, drug development, and materials science. The Fmoc group serves as a protective moiety, shielding the amino group of amino acids to prevent unwanted reactions during chain assembly. The synthesis strategy involves temporarily attaching the Fmoc group to the amino group of an amino acid, followed by sequential removal and addition of amino acid residues to extend the pept......

• • Multiomic Sequencing

  Multiomic sequencing is a method for integrating and analyzing data from various biological molecular omics, including genomics, transcriptomics, proteomics, and metabolomics. Its applications are vast, encompassing areas such as disease mechanism research, drug discovery, precision medicine, and agricultural enhancement. By employing multiomic sequencing, researchers can gain a comprehensive understanding of biological systems, facilitating insights into the functional dynamics and changes in organis......

• • Single Nuclei Sequencing

  Single nuclei sequencing is a genomic or transcriptomic analysis technique focused on individual cell nuclei, particularly advantageous in contexts where isolating intact cells is challenging or where samples are prone to damage during cell separation. Unlike traditional single-cell sequencing, this method efficiently analyzes nuclei without requiring whole cells, making it highly compatible with various sample types. This is particularly beneficial for biological samples like brain tissue or skeletal......