Resources
Proteomics Databases
Metabolomics Databases
-
Antibody sequence analysis is a method used to comprehensively determine and characterize the amino acid sequences of antibody molecules through advanced biotechnological approaches. Antibodies, as protein molecules produced by the immune system, specifically recognize and bind to antigens, playing a critical role in immune defense mechanisms. In biomedical research, drug development, and disease diagnostics, antibodies are indispensable tools. However, the structural complexity and diversity of antib......
-
• Antibody Characterization Techniques
Antibody characterization techniques encompass a comprehensive set of modern bioanalytical methods designed to systematically analyze and characterize the sequence, structure, modifications, affinity, and functional properties of antibody molecules. As essential components of the immune system, antibodies play an irreplaceable role in fundamental research, disease diagnostics, and the development of therapeutic antibody drugs. With the rapid advancement of biopharmaceutical technologies, innovative th......
-
mRNA HPLC analysis is a precise analytical method for separating, identifying, and quantifying mRNA samples. By combining the separation efficiency of high-performance liquid chromatography (HPLC) with advanced detection techniques, this method provides detailed insights into the molecular structure and purity of mRNA. In response to the rapid growth of mRNA-based technologies, HPLC analysis has become an indispensable tool in quality control for mRNA drug development, vaccine research, and gene thera......
-
• N-Terminal Protein Sequencing
N-terminal protein sequencing is a widely used method for determining the amino acid sequence at the N-terminus of a protein. By analyzing the initial amino acid residues of a protein chain, this technique reveals crucial information about protein structure and function, providing insights into biological roles, post-translational modifications, processing mechanisms, and domain architecture. It plays an essential role in proteomics, drug discovery, and biomedical research, particularly in protein str......
-
• Co-Immunoprecipitation (Co-IP)
Co-immunoprecipitation (Co-IP) is a well-established technique extensively used in biochemical and molecular biology research to isolate and study target proteins and their interaction partners from complex biological mixtures. The method is based on the specific antigen-antibody interaction, enabling the selective enrichment and purification of target proteins. By leveraging the high specificity and affinity of antibodies, Co-IP effectively isolates target antigens from cell lysates, tissue homogenat......
-
De novo antibody sequencing is an advanced analytical technique that leverages high-resolution mass spectrometry (HRMS) and bioinformatics tools to accurately determine the complete amino acid sequence of antibodies. Unlike conventional genomic sequencing or antibody gene library methods, this approach directly analyzes the protein sequence, enabling precise sequence determination without relying on genetic templates. This capability addresses the challenges of recognizing antibody variable regions (C......
-
• Protein Analysis Mass Spectrometry
Protein analysis mass spectrometry is a highly precise analytical technique used for the comprehensive study and identification of proteins. Proteins are essential biomolecules that carry out diverse functions in living organisms, including catalyzing biochemical reactions, providing structural support, transmitting cellular signals, and regulating gene expression. Protein analysis mass spectrometry enables scientists to investigate protein structure, function, and interactions with exceptional accura......
-
SEC protein purification, short for size-exclusion chromatography, is a widely used technique for separating and purifying proteins, nucleic acids, and other biological macromolecules based on their molecular size differences. At its core, SEC protein purification relies on a column packed with a porous stationary phase. Molecules traverse the column at rates determined by their ability to diffuse into the pores of the matrix. Larger molecules, which cannot penetrate the pores, elute more rapidly, whi......
-
Post-translational modification proteomics (PTMs proteomics) is a specialized research field dedicated to investigating chemical modifications occurring after protein synthesis and their functional roles within cellular systems. Protein functionality is determined not only by their amino acid sequences but also by the type, location, and dynamic regulation of post-translational modifications (PTMs). These chemical modifications, including phosphorylation, acetylation, methylation, ubiquitination, and ......
-
Kinase profiling is a widely used methodology for investigating the activity of protein kinases and their regulatory roles in cellular signal transduction. Protein kinases are enzymes that catalyze the transfer of phosphate groups from ATP to specific substrate molecules, a process known as phosphorylation. This post-translational modification serves as a fundamental regulatory mechanism in various biological processes, including signal transduction, metabolic regulation, and cell cycle progression. C......
How to order?
