Carbohydrate Analysis Services
- Raw data files from LC-MS, GC-MS, or NMR platforms
- Processed quantitative and identification tables in CSV or Excel format
- Analytical reports in PDF format including methodology, quality control, and key findings
- High-resolution figures and chromatograms in TIFF or PNG format
- Natural Sources: Plant tissues, food materials, fermentation products
- Biological Samples: Serum, cell lysates, tissue extracts
- Purified Samples: Monosaccharides, polysaccharides, glycoconjugates, and standards
MtoZ Biolabs provides professional carbohydrate analysis services integrating multiple analytical platforms, including high-performance liquid chromatography (HPLC), gas chromatography (GC), mass spectrometry (MS), and nuclear magnetic resonance (NMR). These services enable comprehensive characterization and quantitative analysis of polysaccharides, oligosaccharides, monosaccharides, and glycoconjugates. Our analyses deliver high-precision and reproducible data to support clients in food science, biopharmaceuticals, plant research, and materials science, facilitating research and product development.
What are Carbohydrates
Carbohydrates are among the most abundant organic compounds in nature, including monosaccharides, oligosaccharides, polysaccharides, and glycoconjugates. They serve not only as a primary energy source but also play essential roles in cell recognition, signal transduction, immune responses, and biomaterial formation. Through systematic carbohydrate analysis, researchers can elucidate the relationship between structure and function, providing key insights into disease mechanisms, drug development, and food improvement.
Figure 1. Classification of Carbohydrates
Carbohydrate Analysis Services at MtoZ Biolabs
MtoZ Biolabs offers a comprehensive range of carbohydrate analysis services covering all levels from basic sugar units to complex glycoconjugates.
| Starch Analysis Service | Polysaccharide Analysis Service | Monosaccharide Analysis Service |
| Disaccharide Analysis Service | Glycoconjugate Analysis Service |
Our Analytical Platforms Include:
High-Performance Liquid Chromatography (HPLC)
HPLC is used for the separation and quantification of carbohydrate molecules, offering robust glycan profiling and efficient analysis of both simple and complex carbohydrate mixtures. It is particularly well-suited for routine analysis of oligosaccharides and monosaccharides.
Gas Chromatography (GC)
GC is a highly effective method for the analysis of volatile carbohydrates. It is commonly used for the analysis of monosaccharides and their derivatives after derivatization, enabling accurate quantification and detailed structural characterization.
Mass Spectrometry (MS)
Our mass spectrometry platforms, including LC-MS/MS and MALDI-TOF MS, are integral to identifying carbohydrate structures, mapping glycosylation sites, and quantifying glycoconjugates. These platforms provide high sensitivity and resolution, crucial for analyzing complex carbohydrate samples in research and therapeutic applications.
Nuclear Magnetic Resonance (NMR) Spectroscopy
NMR spectroscopy provides detailed structural information about carbohydrate molecules. It is instrumental in elucidating glycan composition, glycosidic linkages, and the specific glycosylation sites within glycoconjugates.
Bioinformatics Analysis
Advanced data processing and bioinformatics tools are used to analyze the data from our platforms, producing comprehensive reports that include structural elucidation and quantitative analysis of carbohydrate components.
Workflow of Carbohydrate Analysis Services
Couture, G. et al. Nat Protoc. 2024.
Figure 2. Comprehensive Analysis of Carbohydrates in Food and Feces
Why Choose MtoZ Biolabs
☑️ Integrated Multi-Platform Analysis: MtoZ Biolabs combines HPLC, GC, LC-MS/MS, NMR, and light scattering technologies to achieve comprehensive detection from trace monosaccharides to complex polysaccharides.
☑️ Experienced Expert Team: Our analysts possess strong backgrounds in glycomics and metabolomics, providing customized solutions tailored to diverse research objectives.
☑️ Customized Analytical Strategies: Based on different sample types and research goals, MtoZ Biolabs designs optimal analytical workflows. From sample preparation to platform selection, every step can be flexibly adapted to achieve targeted and efficient analysis.
Applications of Carbohydrate Analysis Services
1️⃣ Food Science and Nutrition Research: Evaluate carbohydrate composition, digestibility, and nutritional value.
2️⃣ Drug and Biologic Development: Structural confirmation for glycoconjugate drugs, glycoprotein therapeutics, and vaccines.
3️⃣ Plant Metabolism and Agricultural Research: Investigate plant carbon metabolism, cell wall polysaccharides, and stress resistance mechanisms.
4️⃣ Biomaterials and Functional Polysaccharides: Assess structural characteristics and physicochemical properties of polysaccharides.
5️⃣ Metabolomics and Disease Mechanism Studies: Reveal the connection between carbohydrate metabolism abnormalities and metabolic diseases.
Deliverables
1. Detailed experimental report
2. Raw data and chromatograms
3. Data statistics and quality evaluation results
4. Quantitative and structural analysis results
FAQs
Q1: What is the service's general workflow?
Q2: What data formats are provided?
MtoZ Biolabs provides results in multiple standard formats to ensure compatibility with mainstream analytical and visualization tools. Deliverables typically include:
Additional formats or data structures can be provided upon request for specific research or publication requirements.
Q3: How should I prepare my samples?
To ensure accurate and reproducible results, MtoZ Biolabs recommends following the guidelines below:
1. Sample Type: Plant extracts, cell lysates, serum, plasma, tissue samples, and purified standards are accepted.
2. Sample Purity: Samples should be free from particulates and high concentrations of salts, detergents, or organic solvents that may affect chromatographic separation or ionization.
3. Sample Quantity: At least 500 μL of liquid sample or 100 mg of solid material. Additional volume is recommended for replicate analyses.
4. Storage and Shipping: Store biological samples at −80°C and ship on dry ice in leak-proof containers to ensure stability and integrity.
5. Sample Information: Include details such as sample origin, preparation method, buffer composition, and target analysis.
For more information, please refer to Sample Submission Guidelines for Proteomics and Sample Submission Guidelines for Metabolomics.
If you are unsure about your sample preparation, our technical team can provide personalized pre-analysis consultation and a sample submission guide to help you optimize preparation and shipping conditions.
Q4: What types of samples are suitable?
This service is compatible with a wide variety of samples, including:
MtoZ Biolabs analytical platforms can adapt to different sample matrices to ensure accurate and reliable results.
Start Your Project with MtoZ Biolabs
With integrated analytical platforms and extensive experience in carbohydrate research, MtoZ Biolabs offers comprehensive analytical services covering monosaccharides to complex glycoconjugates. We are committed to providing accurate and reliable data to support your research and innovation, serving as a trusted partner for life sciences, food industry, and pharmaceutical studies. For more details or customized quotations, please contact us.
How to order?
