Resources

Proteomics Databases



Metabolomics Databases

• • Determination of Collagen Protein Content in Liquid Phase

  Collagen is an important protein that is widely present in various human tissues, such as skin, bones, muscle tendons, and ligaments. Accurate determination of its concentration is crucial for multiple fields such as biomaterial research, food industry, and pharmaceutical research.

• • The Application of Circular Dichroism in Pharmaceutical Analysis

  Circular Dichroism (CD) uses the absorption properties of optically active substances to analyze the molecular structure of drugs. It has very valuable applications in drug analysis, including:   1. Identification of Drug Stereochemistry Many drug molecules are chiral, and their activity, metabolism, and toxicity can significantly differ due to stereochemistry. CD can differentiate the different chiral forms (enantiomers) of drugs, which is critical to ensuring drug safety and efficacy.

• • Far Ultraviolet Circular Dichroism Spectroscopy

  Circular Dichroism (CD) spectroscopy is a rapid, simple, and accurate method for studying protein structure in dilute solutions. Structural analysis is carried out using the circular dichroism of proteins and the difference in the absorption of left and right circularly polarized light by asymmetric molecules.   The CD spectrum in the far ultraviolet region mainly reflects the circular dichroism of the peptide bond.

• • Average Molecular Weight of Collagen Peptides

  Collagen peptides are a type of small molecule peptide obtained from collagen through enzymatic hydrolysis or other methods. They typically possess a lower molecular weight, which is beneficial for human absorption. The average molecular weight of collagen peptides usually falls within the range of 1000 to 5000 daltons (Da), although this range can vary depending on the production process and the specific requirements of the product.

• • Overview of FT-IR Analysis Technology

  FT-IR analysis, or Fourier Transform Infrared Spectroscopy, is an analytical chemistry technique used to obtain the infrared spectrum of a substance. This technique is primarily used to identify chemical substances or detect the presence of specific compounds.   FT-IR analysis is based on the ability of substance molecules to absorb infrared light at specific wavelengths.

• • Protein Sequencing Requirements for the Sample

  The requirements for samples in protein sequencing usually include the following aspects: 1. Sample Purity The purity of the protein in the sample is crucial. Excessive impurities may interfere with the sequencing results, so various methods (such as centrifugation, filtration, purification, etc.) are usually needed to enhance the purity of the protein.   2. Sample Quantity Different protein sequencing techniques require different amounts of sample.

• • Recombinant Collagen Molecular Weight

  Recombinant collagen is a type of collagen protein expressed in microorganisms, animal cells, or plants through genetic engineering technology. Compared with collagen extracted from natural sources, recombinant collagen has better safety, purity, and controllability, thus it is widely used in the biomedical and cosmetics industries. The molecular weight of recombinant collagen is an important parameter for understanding its structure and function.

• • Can Paraffin Sections Be Sent for Proteomic Sequencing?

  Paraffin sections can be used for proteomic research, but this requires special processing methods. Paraffin sections are usually used for the preservation of tissue samples, which can be used for subsequent DNA, RNA, and protein analysis. However, paraffin itself interferes with protein analysis, so the paraffin needs to be removed before proteomic analysis.

• • Is DDA Considered as Untargeted Quantitative Proteomics?

  DDA (Data-Dependent Acquisition) is one of the methods of non-labeled quantitative proteomics. In proteomic research, quantitative methods are roughly divided into two categories: labeled quantification and non-labeled quantification. DDA is a commonly used non-labeled quantitative method that relies on the data-dependent mode of the mass spectrometer to select specific precursor ions for further fragment analysis.

• • What Is the Specification for Protein Quantification Label?

  Protein quantitative tags, such as Tandem Mass Tag (TMT) and Isobaric Tags for Relative and Absolute Quantitation (iTRAQ), are chemical labels used in mass spectrometry analysis. They allow the simultaneous quantitative comparison of protein expression in multiple samples. These tags are covalently attached to peptides in the sample and detected and quantified during mass spectrometry analysis by releasing a reporter ion.