Proteomics Service
- Dynamic Analysis of Post-Translational Modifications
- Protein Interaction Network Mapping
- Integrated Multi-Omics Analysis
Proteomics Service provides customers with full-process services such as protein identification, quantitative analysis, post-translational modification detection, and protein interaction analysis through standardized experimental processes and high-end mass spectrometry platforms, in order to systematically reveal the composition, function, and dynamic changes of proteins in samples.
As the primary functional molecules in living systems, proteins are responsible for essential physiological processes such as maintaining cellular structure, signal transduction, metabolic regulation, and immune recognition. To truly understand how biological systems operate, it is critical to study protein expression, modifications, interactions, and functional changes under various conditions.
Proteomics is the scientific study of the complete set of proteins-known as the proteome-within a biological system. It focuses on profiling protein expression, structural characteristics, post-translational modifications, subcellular localization, interaction networks, and functional annotation. As a high-throughput, multidimensional systems biology approach, proteomics is often integrated with transcriptomics, metabolomics, and other omics data. It plays a vital role in basic life science research, biomarker discovery, target identification, and drug mechanism studies.
Graves PR. et al. Microbiol Mol Biol Rev. 2022.
Figure 1. Types of proteomics and their applications to biology.
Services at MtoZ Biolabs
Leveraging advanced high-resolution mass spectrometry platforms and sophisticated proteomics sample preparation and data analysis systems, MtoZ Biolabs offers comprehensive and precise proteomics services encompassing whole-proteome characterization, differential expression analysis, post-translational modification detection, protein interaction studies, and targeted protein quantification (PRM/MRM), adapting to diverse sample types and research needs. Combining multi-omics integration with professional bioinformatics support (Proteomics Bioinformatics Analysis Service), MtoZ Biolabs is committed to providing clients with high-quality, high-throughput, and publishable proteomics solutions to advance basic research, disease mechanism analysis, and biomarker discovery.
In addition, MtoZ Biolabs provides a wide range of specialized proteomics-related services, including but not limited to:
Comprehensive protein profiling of fecal samples using high-resolution mass spectrometry to uncover functional biomarkers and molecular insights related to gastrointestinal health and disease.
Cancer Biomarker Discovery Solutions
It integrates multiple platforms and advanced technologies to help identify and validate potential biomarkers for early detection, prognosis and personalized treatment.
4D Proteomics and Dual-Platform Full-Spectrum Metabolomics
Combining four-dimensional proteomics and dual-platform full-spectrum metabolomics, it achieves multi-dimensional and multi-component molecular-level collaborative analysis, which is suitable for mechanism research and integrative omics modeling.
Immunopeptidome Profiling Service
High-throughput identification and lineage analysis of MHC-presented peptides, supporting immunology-focused applications such as vaccine development, tumor immunotherapy, and neoantigen discovery.
Drug Target Identification Solutions
Integrates proteomics, metabolomics, and genomics to investigate disease-relevant tissues or cells, enabling the identification of potential drug targets.
Megger DA. et al. J Clin Transl Hepatol. 2014.
Figure 2. A generalized workflow of a proteomics experiment.
Service Advantages
Advanced Analysis Platform: MtoZ Biolabs established an advanced Proteomics Service platform, guaranteeing reliable, fast, and highly accurate analysis service.
One-Time-Charge: Our pricing is transparent, no hidden fees or additional costs.
High-Data-Quality: Deep data coverage with strict data quality control. AI-powered bioinformatics platform integrates all Proteomics data, providing clients with a comprehensive data report.
Compatibility with Diverse Sample Types: Capable of processing a wide range of biological materials, including tissues, cells, blood, urine, feces, and exosomes, meeting the needs of both basic and preclinical research.
Customized Projects and End-to-End Workflow Management: Offers a fully integrated, one-stop service covering experimental design, sample preparation, mass spectrometry analysis, and data reporting, with flexible customization to support specific research goals.
Applications
Applications of the Proteomics Service include, but are not limited to:
Monitor changes in post-translational modifications such as phosphorylation, acetylation, and ubiquitination under different conditions to explore the regulatory mechanisms of protein activity and signaling pathways.
Identify protein complexes and their interactions, and construct functional network maps of biological processes.
Integrate with transcriptome and metabolome data to conduct systems biology studies and reveal molecular-level coordinated regulatory mechanisms.
Deliverables
1. Comprehensive Experimental Details
2. Materials, Instruments, and Methods
3. Total Ion Chromatogram & Quality Control Assessment (project-dependent)
4. Data Analysis, Preprocessing, and Estimation (project-dependent)
5. Bioinformatics Analysis
6. Raw Data Files
Related Services
How to order?
