Peptide Drug Physicochemical Profiling Service

MtoZ Biolabs provides comprehensive Peptide Drug Physicochemical Profiling Service to evaluate the inherent physical and chemical properties that influence peptide drug solubility, stability, manufacturability, and overall developability. Peptide therapeutics often show sensitivity to pH, temperature, oxidation, and aggregation due to their structural flexibility and amphiphilic characteristics. These factors directly impact formulation design, dosing accuracy, bioavailability, and long-term storage. Our profiling service offers the essential data required to advance peptide drug candidates with confidence.

 

Overview

A peptide’s physicochemical properties, including solubility, charge state, hydrophobicity, pKa, and aggregation behavior, are determined by its sequence composition, conformational flexibility, and environmental conditions such as pH and ionic strength.

 

MtoZ Biolabs integrates analytical chemistry, biophysical characterization, and computational assessment to measure these properties using HPLC, LC-MS, UV-Vis spectroscopy, DLS, CE, CD, and permeability assays. By combining thermodynamic and kinetic insights, we provide data-driven guidance for structural refinement, developability assessment, and formulation planning.

 

Peptide Drug Physicochemical Profiling Service at MtoZ Biolabs

MtoZ Biolabs offers a broad suite of physicochemical assays to support peptide drug development. Available services include:

● Net Peptide Content Determination Service

● Peptide Charge Identification Service

● Peptide Solubility Testing Service

● Peptide Stability Testing Service

● Peptide Impurity and Degradation Product Analysis Service

These services can be conducted independently or combined into an integrated profiling package tailored to your program’s needs.

 

Why Choose MtoZ Biolabs?

✅ Comprehensive Profiling Capabilities: A full panel of solubility, stability, charge, and impurity analyses designed specifically for peptide therapeutics.

✅ Advanced Analytical Platforms: High-resolution LC-MS, electrophoresis, and biophysical tools ensure precise, reliable characterization.

✅ Peptide-Specific Expertise: Our scientific team understands the unique challenges associated with peptide drug design and development.

✅ Flexible Service Design: Clients can select individual assays or build integrated profiling strategies aligned with development goals.

✅ One-Time-Charge: Our pricing is transparent, no hidden fees or additional costs.

 

Start Your Project with MtoZ Biolabs

MtoZ Biolabs delivers an integrated physicochemical profiling solution designed to advance peptide drug developability, ensure formulation readiness, and support successful downstream scientific evaluation.

 

Contact us to obtain a customized profiling plan tailored to your peptide program.

 

FAQ

Q1: What types of samples are suitable?

We support linear, cyclic, stapled, modified, lipidated, PEGylated, and formulated peptides. Complex or hydrophobic peptides are also accepted.

 

Q2: What is the service general workflow?

 

 

Q3: What data formats are provided?

You will receive a detailed PDF report, Excel data tables, spectra, chromatograms, and any biophysical outputs. Raw files are available upon request.

 

Q4: How should I prepare my samples?

Peptide samples should have ≥90 percent purity and be provided as dry powders or dissolved in compatible solvents. Please provide 1-2 mg of material, labeled and packaged securely. We can provide detailed submission instructions on request.

 

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