Resources

Proteomics Databases



Metabolomics Databases

• • Proteomics: From Quantification to Functional Insights

  Basic Concepts of Proteomics Proteomics is a crucial branch of biology that investigates all the proteins within an organism, including their structure, function, and interactions. These proteins constitute the organism's "proteome," and they are the main executors of biological activities.   Quantitative Analysis in Proteomics Quantitative proteomics is an essential field within proteomics that focuses on accurately measuring the relative or absolute abundance of each protein in a cell. With the aid ......

• • Methods for Protein Content Determination

  Protein content determination is a significant research topic in the fields of biochemistry and food science. There are various methods available to determine the protein content in samples, each with its specific application scenarios and advantages and disadvantages. Below is a detailed introduction to several common methods for protein content determination:   Kjeldahl Method 1. Principle The Kjeldahl method is a classic technique for protein content determination. It estimates protein content indi......

• • High Throughput Screening in Genome for Drug Discovery

  Introduction: Where Do Targets Come From? In the field of high throughput screening in genome for drug discovery, identifying a truly effective therapeutic target is often more challenging than discovering an active compound. With the rapid advancement of gene-editing technologies such as CRISPR and RNA interference (RNAi), researchers are now capable of conducting systematic gene knockout, activation, or suppression at the whole-genome level. This enables the identification of genes crucial to diseas......

• • High Throughput Screening Significance in Drug Discovery

  Introduction: Core Technologies Transforming the Drug Development Paradigm The high throughput screening significance in drug discovery has become increasingly prominent as it redefines the traditional landscape of pharmaceutical research and development. Serving as a core engine of modern drug discovery, high throughput screening (HTS) enables the rapid assessment of biological activity across vast compound libraries by integrating automated technologies. This transformative approach significantly sh......

• • Zebrafish High Throughput Screening

  Zebrafish High Throughput Screening is a rapidly emerging technology in the fields of biomedical research and drug development. As a vertebrate model, zebrafish combines the high-throughput capabilities of in vitro experiments with the systemic physiological advantages of mammalian models, making it an ideal bridge between basic research and clinical applications. The core of zebrafish high throughput screening lies in utilizing its biological characteristics—embryonic transparency, rapid development ......

• • Quantitative Proteomics Techniques

  In modern life science research, merely identifying the presence of proteins is no longer sufficient. Scientists are increasingly concerned with deeper questions: How much is a protein expressed? What are its dynamic trends? Is it involved in disease pathogenesis? Addressing these questions requires the power of quantitative proteomics techniques. These approaches not only comprehensively identify the proteins present in a sample but also precisely measure their expression levels, making them indispen......

• • Organoid High Throughput Screening

  Organoid high throughput screening represents a revolutionary upgrade in the development of in vitro models. Conventional cell lines, while enabling high-throughput analysis, lack the native microenvironment and three-dimensional (3D) structure required to faithfully replicate human disease. Animal models, though physiologically relevant, remain constrained by high costs, extended timelines, and ethical barriers. The emergence of organoids overcomes these limitations. Derived from stem cells or tissue......

• • High Throughput Screening (HTS) Significance in Drug Discovery

  The high throughput screening (HTS) significance in drug discovery cannot be overstated, as it is integral to the identification and optimization of potential drug candidates. Before the successful development of a new drug, it typically must emerge from an initial pool of millions of candidate molecules. This process resembles isolating a single pearl from the depths of an ocean. One of the pivotal technologies enabling this formidable task is high throughput screening (HTS). As the foundational step......

• • Drug Discovery High Throughput Screening

  Drug discovery high throughput screening is a cornerstone technology in modern pharmaceutical research. It enables the systematic and rapid evaluation of thousands to millions of small molecules, biomolecules, or natural products for potential biological activity using automated platforms and large-scale experimental systems. By integrating robotics, micro-volume liquid handling, multiplexed detection systems, and data analytics, drug discovery high throughput screening significantly enhances the effi......

• • High Throughput Compound Screening

  High throughput compound screening is a pivotal technology designed for the rapid evaluation and identification of biologically active compounds from large-scale chemical libraries. This technique enables the screening of thousands to millions of compounds within a short time frame, making it indispensable in the early stages of drug discovery. Pharmaceutical companies and research institutions leverage this approach to systematically examine vast compound collections, aiming to identify chemical enti......