Protein Composition Analysis Service
- Comprehensive Protein Identification: Precisely identify all protein components in complex samples using high-sensitivity LC-MS/MS.
- Accurate Protein Quantification: Evaluate protein content and proportions via absolute or relative quantification approaches.
- Detailed PTM Analysis: Identify and localize modifications such as phosphorylation and glycosylation with high precision.
- Protein Complex Analysis: Analyze the subunit composition and relative proportions within protein complexes.
- Non-Protein Interactions: Detect protein interactions with metal ions, cofactors, or small molecules.
- Structural biology: Supports protein structural and functional studies with precise composition and modification data.
- Drug development: Facilitates drug discovery by analyzing target protein composition and modifications.
- Quality control: Ensures the consistency and purity of biologics through rigorous protein analysis.
- Food science: Evaluates food-derived proteins for nutritional and functional properties.
- Disease research: Tracks protein changes to uncover disease mechanisms and biomarkers.
Protein composition analysis is a critical technique for studying protein types, quantities, and modifications in biological samples. Widely applied in basic research, biopharmaceuticals, and clinical diagnostics, it enables the exploration of molecular mechanisms in cellular signaling, metabolic regulation, and protein interactions, offering invaluable insights for disease diagnosis and drug development.
MtoZ Biolabs provides cutting-edge Protein Composition Analysis Service, backed by advanced technologies and extensive expertise. Leveraging high-resolution mass spectrometry (e.g., LC-MS/MS) and sophisticated separation methods (e.g., 2D electrophoresis, gel filtration), we deliver accurate, reliable, and customized analysis solutions for both research and industry applications.
Services at MtoZ Biolabs
Through our protein composition analysis service, we offer a suite of specialized solutions designed to tackle diverse protein analysis challenges. With advanced methodologies and a focus on precision, our services are tailored to meet the unique needs of every project.
Analysis Workflow
1. Sample Preparation: Pre-treatment tailored to analytical needs, including hydrolysis and enzymatic digestion.
2. Separation and Detection: Advanced techniques such as LC, GPC, and IEF ensure effective separation.
3. Mass Spectrometry: High-resolution systems like Orbitrap and FTICR MS deliver precise identification and molecular weight determination.
4. Data Analysis: Comprehensive interpretation using specialized databases and analysis tools.
5. Report Delivery: Detailed reports covering workflows, results, and expert insights.
Why Choose MtoZ Biolabs?
1. Advanced Analysis Platform: MtoZ Biolabs integrates MS, GPC, and IEF technologies into a comprehensive platform, delivering multi-dimensional and detailed protein component analysis with exceptional reliability, speed, and precision.
2. Broad Sample Compatibility: Our platform accommodates various biological samples—from purified proteins to complex matrices like cell lysates, tissues, and bodily fluids—to meet diverse research needs.
3 High-Data-Quality: Deep data coverage with strict data quality control. AI-powered bioinformatics platform integrate all proteomics analysis data providing clients with a comprehensive data report.
4. Customized Service: Tailored to the specific research needs of our clients, we offer flexible experimental design and personalized data analysis to ensure the achievement of research goals to the fullest extent.
5. One-Time-Charge: Our pricing is transparent, no hidden fees or additional costs.
Applications
Case Study
1. LC-MS/MS-Based Protein Component Analysis of Extracted Yeast Cells
Michelot, A. et al. Curr. Biol. 2010.
FAQ
Q1: Can low-abundance proteins in complex samples be analyzed?
Yes, MtoZ Biolabs employs high-sensitivity platforms like Orbitrap Fusion Lumos and Nano-LC systems, alongside advanced enrichment strategies, to achieve precise detection of low-abundance proteins. Custom protocols ensure reliable, high-quality results tailored to your research needs.
Deliverables
1. Comprehensive Experimental Details
2. Materials, Instruments, and Methods
3. Total Ion Chromatogram & Quality Control Assessment
4. Data Analysis, Preprocessing, and Estimation
5. Bioinformatics Analysis
6. Raw Data Files
MtoZ Biolabs, an integrated Chromatography and Mass Spectrometry (MS) Services Provider, provides advanced proteomics, metabolomics, and biopharmaceutical analysis services to researchers in biochemistry, biotechnology, and biopharmaceutical fields. Our Protein Composition Analysis Service is designed to provide high-throughput, cost-effective solutions with exceptional data quality and minimal sample consumption. Free project evaluation, welcome to learn more details.
How to order?
