Protein β-Hydroxybutyrylation Analysis

β-Hydroxybutyrylation (Kbhb), a novel PTM, occurs under conditions of β-hydroxybutyrate (BHB) accumulation and involves the covalent attachment of a β-hydroxybutyryl group to lysine residues. This modification plays a key role in regulating energy metabolism, gene expression, and stress response.

MtoZ Biolabs provides specialized Protein β-Hydroxybutyrylation Analysis designed to support researchers in accurately detecting and characterizing this important post-translational modification across a wide range of biological samples. By integrating β-hydroxybutyrylation-specific enrichment strategies with high-resolution LC-MS/MS, our platform enables both targeted analysis of individual proteins and large-scale proteomic profiling of β-hydroxybutyrylation events.

This analysis service effectively addresses key analytical challenges, including low modification abundance, complex sample backgrounds, and the difficulty of pinpointing modification sites, ensuring that all results are highly reliable and reproducible. MtoZ Biolabs provides strong technical support for studies exploring the role of β-hydroxybutyrylation in energy metabolism regulation, epigenetic mechanisms, and disease-associated signaling pathways.

Services at MtoZ Biolabs

1. Target protein β-hydroxybutyrylation analysis

MtoZ Biolabs provides Target Protein β-Hydroxybutyrylation Analysis, offering specific detection of β-hydroxybutyrylation (Kbhb) modifications on client-designated proteins. By integrating immunoprecipitation (Co-IP) with high-resolution mass spectrometry (LC-MS/MS) and employing anti-Kbhb–specific antibodies for efficient enrichment of modified proteins or peptides, this service enables precise identification of modification sites and quantitative assessment of modification levels. It is suitable for investigating the β-hydroxybutyrylation status of specific proteins, providing reliable experimental support for mechanistic studies and functional validation.

2. β-hydroxybutyrylation proteomics analysis

If you are interested in our protein β-hydroxybutyrylation analysis service, please feel free to contact us. We are dedicated to providing you with the best service.

Analysis Workflow

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Service Advantages

1. Advance Analysis Platform: Mtoz Biolabs established an advanced protein β-hydroxybutyrylation analysis platform, guaranteeing reliable, fast, and highly accurate analysis service.

2. One-Time Charge: Our pricing is transparent, with no hidden fees or additional costs.

3. High-Data-Quality: Deep data coverage with strict data quality control. AI-powered bioinformatics platform integrate all protein β-hydroxybutyrylation analysis data providing clients with acomprehensive data report.

4. Comprehensive Analysis: Both target protein β-hydroxybutyrylation analysis and β-hydroxybutyrylation proteomics can be conducted in MtoZ Biolabs.

Sample Submission Requirements

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1. If you are providing tissue samples, please ship them to us on dry ice.

2. If you are providing protein samples, standard tissue or cell lysis buffers can be used during protein extraction.

3. Sample transportation: Please ensure that samples are shipped with sufficient dry ice and choose the fastest possible shipping way to minimize the risk of sample degradation during transit.

4. Before proceeding with the formal experiment, we will test the samples you provide, and the formal analysis will begin once the samples pass the quality check.