Integrated Peptidomics and Transcriptomics Analysis Service
- Precise peptide identification using high-resolution LC-MS/MS platforms (DDA, DIA modes)
- Quantitative peptide profiling using TMT, iTRAQ, or label-free methods
- Comprehensive characterization of post-translational modifications including phosphorylation and glycosylation
- High-throughput RNA sequencing on Illumina platforms covering mRNA, lncRNA, miRNA, and other transcript types
- Analysis of RNA modifications such as methylation to explore post-transcriptional regulation
Understanding the complex relationship between gene expression and peptide-level regulation is essential for advancing cell biology and disease research. Peptidomics focuses on identifying and quantifying biologically active peptides, many of which originate from protein precursors and play critical roles in signaling, immunity, and metabolic control. Transcriptomics, on the other hand, reveals how genes are turned on or off under different physiological and pathological conditions by profiling RNA molecules such as mRNA, lncRNA, and miRNA.
By integrating these two complementary datasets, researchers can gain deeper insight into how peptides and transcripts interact to regulate cellular functions and influence disease progression. MtoZ Biolabs offers comprehensive Integrated Peptidomics and Transcriptomics Analysis Service powered by high-resolution mass spectrometry and Illumina-based RNA sequencing to support biomarker discovery, drug target identification, and functional mechanism studies.
Services at MtoZ Biolabs
1. Peptidomics Analysis
2. Transcriptomics Analysis
3. Multi-Omics Data Integration
We integrate peptide and transcriptomic data to explore the correlation between peptide abundance and gene expression. This combined analysis reveals coordinated regulation, functional pathways, and molecular networks, supporting deeper insights into disease mechanisms and therapeutic targets.
Analysis Workflow
MtoZ Biolabs provides an end-to-end analysis pipeline covering both peptidomics and transcriptomics, with seamless integration of the two data layers:
1. Sample Preparation
Peptides and RNA are extracted from biological sources such as cells, tissues, plasma, or urine. Enrichment and purification are performed using ultrafiltration and solid-phase extraction to ensure sample quality and consistency.
2. Mass Spectrometry Analysis
Peptide samples are analyzed on LC-MS/MS systems including Orbitrap Fusion Lumos and Q Exactive for high-resolution, high-sensitivity detection.
3. RNA Sequencing
Illumina-based RNA-seq captures gene expression with high throughput and base-level precision, generating a comprehensive transcriptome dataset.
4. Data Integration and Analysis
We apply advanced bioinformatics tools to merge peptidomic and transcriptomic data. Correlation analysis and pathway mapping reveal functionally connected molecular mechanisms and regulatory axes.
5. Structured Reporting
Clients receive a comprehensive report featuring peptide and gene quantification, differential expression analysis, PTM mapping, and pathway annotations with detailed biological interpretations.
Why Choose MtoZ Biolabs?
✔ State-of-the-art Platforms: We use Orbitrap Fusion Lumos and Q Exactive mass spectrometers for peptidomics, and Illumina sequencing systems for transcriptomics, ensuring both sensitivity and throughput.
✔ Versatile Sample Support: Compatible with various biological matrices including tissues, cells, blood, and urine.
✔ Tailored Solutions: Customized study designs to match your research goals, whether for drug discovery, disease mechanism exploration, or personalized therapy development.
✔ One-Time-Charge: Our pricing is transparent, no hidden fees or additional costs.
Sample Submission Suggestions
Note: Provide details on sample collection and handling. If you need further details, our technical support team is happy to assist and provide comprehensive guidance on sample submission.
MtoZ Biolabs’ Integrated Peptidomics and Transcriptomics Analysis Service combines peptide and gene expression profiling to reveal molecular mechanisms underlying disease, identify therapeutic targets, and support personalized treatment strategies. This approach also enables early diagnosis and monitoring of treatment response.
With a strong focus on scientific accuracy and customized support, MtoZ Biolabs delivers integrated multi-omics solutions that provide deep molecular insights into cellular function and disease biology. To explore how this service can support your research, contact our team for expert guidance and tailored project plans.
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