Integrated Peptidomics and Lipidomics Analysis Service
Peptides and lipids are essential biological molecules in life science research, playing critical roles inside and outside the cell. They are central to cellular signaling, metabolic regulation, and cell function and influence multiple physiological processes through their interactions. Peptides often cooperate with lipids to stabilize cell membranes, transmit receptor signals, and regulate immune responses.
MtoZ Biolabs' Integrated Peptidomics and Lipidomics Analysis Service offers a comprehensive view of peptide–lipid interactions by integrating advanced mass spectrometry with liquid and gas chromatography systems. Through multi-omics data fusion, this service provides high-quality analytical support for basic research, clinical investigation, and pharmaceutical development.
Services at MtoZ Biolabs
MtoZ Biolabs offers a complete suite of integrated peptidomics and lipidomics analysis services, including but not limited to:
1. Peptidomics Analysis
Peptide Sequence Analysis: We use high-resolution mass spectrometry technologies (DDA and DIA modes) to identify peptide sequences with high precision.
Peptide Quantification: Peptides are quantified using both label-free and labeled quantification techniques to measure changes in peptide abundance under various physiological and pathological conditions.
Post-Translational Modification (PTM) Analysis: We identify PTMs such as phosphorylation, glycosylation, and acetylation and investigate their role in functional regulation.
2. Lipidomics Analysis
Lipid Type Identification and Quantification: We use LC-MS/MS and GC-MS to identify and quantify various lipid species, such as phospholipids, sphingolipids, and triglycerides.
Lipid Post-Translational Modification Analysis: We study PTMs on lipid molecules, exploring their diverse roles in cellular signaling and metabolism.
3. Integrated Peptidomics and Lipidomics Analysis
Peptide-Lipid Complex and Function Prediction: We use mass spectrometry to analyze the binding between peptides and lipids and combine computational modeling and bioinformatics analysis to identify interaction sites and mechanisms.
Cross-analysis and Pathway Enrichment: We perform cross-analysis of peptide and lipid changes and use bioinformatics tools to identify related metabolic pathways, uncovering how peptides and lipids interact and regulate cellular processes.
Analysis Workflow
Our Integrated Peptidomics and Lipidomics Analysis Service follows a structured, rigorous process to ensure high-quality data and accurate analysis:
1. Sample Preparation and Processing
We extract peptides and lipids from cells, tissues, or biological fluids, using ultrafiltration and solid-phase extraction to enrich and purify the samples.
2. LC-MS/MS Analysis
We separate peptides and lipids and analyze them using high-resolution mass spectrometry systems like Orbitrap, Q-TOF, and others to ensure accurate detection.
3. Data Processing and Analysis
We analyze data with advanced software tools (MaxQuant, Proteome Discoverer, Spectronaut) and use bioinformatics tools for functional annotation and pathway analysis.
4. Results Reporting
We provide structured reports that include peptide sequences, lipid species, quantitative data, PTM information, and functional annotations.
Why Choose MtoZ Biolabs?
MtoZ Biolabs' Integrated Peptidomics and Lipidomics Analysis Service offers several advantages:
✔ Advanced Analysis Platform: We use high-end systems like Orbitrap Fusion Lumos, Q Exactive, and TimsTOF for high sensitivity and broad dynamic range.
✔ Multi-Platform Integrated Analysis: Combining LC-MS/MS, GC-MS, NMR, and FT-IR ensures comprehensive peptide and lipid identification and quantification.
✔ High-Data-Quality: Deep data coverage with strict data quality control. AI-powered bioinformatics platform integrate all analysis data, providing clients with a comprehensive data report.
✔ Customized Service Plans: We tailor analysis plans to your research needs, ensuring flexibility for different experimental objectives.
✔ One-Time-Charge: Our pricing is transparent, no hidden fees or additional costs.
Sample Submission Suggestions
Note: Provide details on sample collection and handling. If you need further details, our technical support team is happy to assist and provide comprehensive guidance on sample submission.
Applications
Our Integrated Peptidomics and Lipidomics Analysis Service is applicable across various research and application fields, including but not limited to:
· Drug Development: Exploring the roles of peptides and lipids in diseases, identifying new targets, and supporting drug development.
· Metabolic Research: Analyzing peptide-lipid metabolic pathways to understand changes in metabolism and their role in disease.
· Biomedical Research: Peptide-lipid interactions are critical in numerous physiological and pathological processes, applicable in cancer, neurodegenerative diseases, and other areas.
· Nutritional and Health Supplement Development: Functionally analyzing peptides and lipids to develop new nutritional supplements and optimize formulations.
· Cosmetic R&D: Developing new anti-aging, anti-inflammatory, and repair ingredients by analyzing peptide-lipid interactions.
FAQ
Q1: Can specific lipids or peptides be analyzed?
Yes. We offer targeted analysis based on client requirements, focusing on specific lipid classes (such as sphingolipids or phospholipids) and post-translationally modified peptides (such as phosphorylated peptides). This enables researchers to concentrate on key biomarkers or disease-associated molecules.
Q2: How is lipid sample stability ensured?
We use a chloroform/methanol extraction method under low-temperature conditions, incorporating antioxidants such as BHT and DTT to prevent lipid degradation. This ensures molecular stability and analytical accuracy throughout the process.
MtoZ Biolabs is committed to delivering comprehensive multi-omics services, spanning peptidomics, lipidomics, metabolomics, and transcriptomics. By integrating data across these platforms, we help researchers uncover complex cellular interactions and advance studies in disease mechanisms, drug development, and biomarker discovery.
To learn more about our Integrated Peptidomics and Lipidomics Analysis Service, please contact us for a free consultation.
What Could be Included in the Report?
1. Comprehensive Experimental Details
2. Materials, Instruments, and Methods
3. Total Ion Chromatogram & Quality Control Assessment
4. Data Analysis, Preprocessing, and Estimation
5. Bioinformatics Analysis
6. Raw Data Files
Related Services
Integrated Peptidomics and Metabolomics Analysis Service
Integrated Peptidomics and Transcriptomics Analysis Service
How to order?
