Exosome Function
- Isolated Exosomes: ≥200 μg total protein or ≥100 μL in PBS
- Plasma/Serum: ≥2 mL per sample
- Cell Culture Supernatants: ≥5 mL per sample
- Other Body Fluids: Please inquire for specific requirements
As intercellular messengers, exosomes have emerged as critical regulators in various physiological and pathological processes, including immune modulation, tumor progression, angiogenesis, neurodegeneration, and tissue repair. While their molecular content—proteins, RNAs, lipids, and metabolites—provides clues to their biological relevance, understanding the actual function of exosomes is essential for translating these vesicles into reliable biomarkers or therapeutic vectors.
Functional analysis of exosomes allows researchers to move beyond descriptive profiling and establish causative roles in cellular communication. This involves determining how exosomes interact with recipient cells, modulate signaling pathways, and influence biological outcomes such as proliferation, migration, apoptosis, or differentiation. Without such functional validation, interpretations of omics data remain speculative. Furthermore, as the biomedical community intensifies efforts to develop exosome-based diagnostics and therapeutics, rigorous assessment of their bioactivity in vitro and in vivo becomes indispensable for clinical translation.
Service at MtoZ Biolabs
MtoZ Biolabs offers a comprehensive Exosome Function Analysis Service built on an integrated workflow that spans from exosome isolation to function validation. Our service includes:
By combining advanced multi-omics with functional readouts, MtoZ Biolabs delivers a powerful platform to help researchers determine the true biological impact of exosomes and generate actionable insights for discovery, validation, and translational application.
Figure 1. In Vitro and In Vivo Functional Assays
Service Advantages
☑️In Vitro & In Vivo Expertise: From cell-based bioassays to animal models, we offer broad assay capabilities.
☑️Customizable Workflow: Flexible design tailored to your sample type, target cells, and research objectives.
☑️Expert Guidance: Our team of cell biologists, immunologists, and data analysts ensures your study is scientifically sound and technically robust.
☑️One-Stop Service: From exosome purification to data interpretation, everything is handled by our technical team to save your time and ensure quality control.
Applications
Exosome Function Analysis Service enables researchers to:
1. Determine exosome bioactivity in cell proliferation, migration, apoptosis, and immune modulation.
2. Uncover mechanisms of disease progression such as tumor invasion, neurodegeneration, or fibrosis.
3. Assess therapeutic potential of engineered or native exosomes for drug delivery or regenerative medicine.
4. Validate exosome-based biomarkers through functional correlation.
Sample Submission Suggestions
We accept the following sample types:
Samples should be stored at -80°C and shipped on dry ice. Avoid repeated freeze–thaw cycles.
*Please consult us for tailored collection and storage protocols to maximize data quality.
Deliverables
1. Experimental report outlining study design and methodology
2. Exosome characterization data (NTA, TEM, Western blot, etc.)
3. Raw and processed data from in vitro/in vivo assays
4. Molecular profiling results (if applicable)
5. Bioinformatics summary and statistical analyses
If you are interested in our Exosome Function Analysis Service, please feel free to contact us. Our technical specialists are available to provide a free business assessment.
How to order?
