Cosmetics Peptide Active Ingredient Discovery Service
- Solid Samples: At least 2 mg
- Liquid Samples: At least 200 µL with a concentration of ≥1 mg/mL
- Raw Cosmetics: At least 2 mL
- Store at -80°C
- Ship using dry ice to prevent repeated freeze-thaw cycles
- Ensure samples are free from protease contamination
- Cosmetics Peptide Active Ingredient Discovery Service is applicable to a wide range of research and applications, including:
- Development of anti-aging peptides (stimulating collagen production and inhibiting elastin degradation)
- Whitening peptide research (inhibiting tyrosinase activity)
- Moisturizing and repair peptide screening (enhancing skin barrier function)
- Anti-inflammatory and soothing peptide identification (reducing irritation and sensitivity)
- Support for new functional peptide ingredient registration (INCI / cosmetic new ingredient filing)
Peptides are rapidly emerging as star ingredients in the next generation of functional skincare, driven by their high specificity, low immunogenicity, and proven biological activities. From signaling peptides that promote collagen synthesis, to carrier peptides that enhance skin penetration, enzyme-inhibiting peptides that prevent degradation, and neurotransmitter-affecting peptides that reduce dynamic wrinkles—the functional classification of cosmetic peptides has become increasingly sophisticated and well-defined. As illustrated below, each peptide category contributes uniquely to skin health and rejuvenation:
Ngoc, L. T. N. et al. Cosmetics. 2023.
Figure 1. Classification of Bioactive Peptides Based on Cosmetic Properties
MtoZ Biolabs offers Cosmetics Peptide Active Ingredient Discovery Service that combines in silico screening, structural-function prediction, mechanism-of-action analysis, and functional validation to support the discovery of innovative and efficacious peptide-based actives. Whether you are developing anti-aging, barrier-repair, or brightening formulations, our platform is designed to accelerate the identification and characterization of bioactive peptides with translational potential for the cosmetics industry.
Services at MtoZ Biolabs
In Cosmetics Peptide Active Ingredient Discovery Service, MtoZ Biolabs offers a comprehensive, systematic approach to peptide active ingredient research for the cosmetics industry, covering the full process from sequence screening to mechanism analysis. Our services include:
1. Active Peptide Sequence Identification
Utilizing LC-MS/MS technology combined with data mining algorithms, we quickly identify potential active peptide sequences from both natural and synthetic samples. Through sample comparison and database annotation, we accurately locate peptides and predict their functions.
2. Peptide Structure Optimization and Activity Enhancement
Using Structure-Activity Relationship (SAR) models, we synthesize and modify candidate peptides to improve their stability, skin penetration, and targeting effects, thus enhancing their functional performance on the skin.
3. Activity Validation and Screening
We conduct high-throughput cell-based assays or in vitro models to evaluate the peptides’ efficacy in antioxidant, anti-inflammatory, and collagen-stimulating activities, while combining toxicology analysis to ensure safety.
4. Mechanism Research and Pathway Analysis
By integrating protein interaction networks and pathway enrichment analysis, we uncover the mechanisms of action of peptide ingredients at the cellular level, providing data support for functional labeling and efficacy claims.
5. Development of Novel Peptide Active Ingredients
We focus on developing innovative functional peptides for specific applications such as anti-aging, brightening, and repair, driving the development of personalized and aesthetic-driven products that meet market demands.
Why Choose MtoZ Biolabs?
✅ Advanced Platform: Powered by Thermo Orbitrap mass spectrometry technology, we offer high-throughput, high-sensitivity capabilities.
✅ Accurate Data: We use a mature data analysis process to ensure the reliability of peptide identification and functional predictions.
✅ Integrated Service: From peptide discovery to functional validation, our services are fully customizable to boost R&D efficiency.
✅ Experienced Team: Our team has extensive experience in cosmetic peptide projects and is well-versed in industry needs and compliance requirements.
Sample Submission Suggestions
To ensure optimal results in the Cosmetics Peptide Active Ingredient Discovery Service, please review the following guidelines before submitting samples:
1. Sample Types:
We accept a variety of samples, including animal tissues, plant extracts, fermentation liquids, recombinant proteins, peptide libraries, and finished cosmetics (e.g., lotions, gels, serums).
2. Recommended Sample Amount:
3. Storage and Transport:
Note: If your samples include complex matrices (e.g., high salt or sugar), please contact MtoZ Biolabs' technical team before submission to devise the best analysis strategy.
Applications
As consumer demand for effective, safe, and functional skincare continues to rise, peptide-based active ingredients are becoming a focal point of the industry. MtoZ Biolabs' Cosmetics Peptide Active Ingredient Discovery Service provides rigorous scientific support, cutting-edge technology, and a comprehensive delivery system to help cosmetics companies and research institutions rapidly advance from raw material discovery to efficacy validation.
Feel free to contact us to begin your peptide ingredient development journey.
FAQ
Q1: How can we increase the detection rate of low-abundance peptides in LC-MS/MS?
We utilize multi-stage enrichment strategies (e.g., reverse-phase-strong cation exchange SPE), combined data-dependent acquisition (DDA) with data-independent acquisition (DIA), and targeted PRM methods to significantly enhance the identification and quantification of low-abundance functional peptides.
What Could be Included in the Report?
1. Comprehensive Experimental Details
2. Materials, Instruments, and Methods
3. Total Ion Chromatogram & Quality Control Assessment
4. Data Analysis, Preprocessing, and Estimation
5. Bioinformatics Analysis
6. Raw Data Files
Related Services
Peptidomics-Based Cosmetic Research Service
Peptide Cosmetic Ingredients Identification Service
Active Ingredients Identification and Screening Service
How to order?
