Resources

Proteomics Databases



Metabolomics Databases

• • Antibody-Drug Conjugates Assay Project

  Antibody-drug conjugates (ADCs) testing includes a series of assays to evaluate the quality, stability, efficacy, and safety of ADCs. These testing assays may include:

• • Cell Histones Peptide Mass Fingerprint Analysis

  Cells, the basic units of life, maintain the fundamental functions of organisms through their intricate mechanisms and interactions. Proteins play a crucial role in these microentities, from catalyzing chemical reactions to transmitting signals and regulating gene expression. However, to gain a deeper understanding of how these proteins collaborate within cells, we need more advanced and precise technological approaches.

• • HPLC Peptide Map Analysis of Fish Tissue

  Fish, as a rich source of protein, is not only an important part of human diet, but also a valuable sample in biomedical research. Fish tissue, mainly composed of the muscle part of fish, is a nutritious food. It is known for its high protein and low fat content, rich in essential amino acids. Fish contains various vitamins and minerals, such as vitamin D, B2, calcium, and phosphorus. Its muscle fibers are short, tender in texture, and easy to digest, making it an indispensable part of a healthy diet.

• • mRNA Cap Efficiency Detection

  mRNA capping efficiency detection is a process used to evaluate the successful addition of a cap structure (typically a 7-methylguanosine triphosphate (m7G) cap) at the 5' end of mRNA molecules. This cap structure is crucial for the stability of mRNA and its translation efficiency within cells. The 5' cap of mRNA plays several key biological functions, including regulating nuclear export, protecting against degradation by exonucleases, and promoting translation.

• • Dynamic Light Scattering (DLS) Analysis of Rat Cells

  Understanding the physical and chemical properties of cells is crucial in biomedical research. As widely used experimental animals, the study of rat cells provides valuable insights into the understanding and treatment of human diseases. Dynamic Light Scattering (DLS) is a widely applied technique for measuring the size distribution of nanoparticles to microparticles in solution.

• • Identification of Plasma Protein by Tandem Mass Spectrometry

  Plasma, a liquid tissue containing rich biological information, serves not only as a medium for nutrient transfer but also as a carrier for important signaling molecules and functional proteins in the body. It encompasses thousands of proteins that play crucial roles in many physiological processes and serve as important sources of disease biomarkers.

• • Flow Cytometry Multiplex Analysis of Mouse Cells

  In biomedical research, mice play a crucial role as model organisms in studying disease mechanisms and drug development. In order to gain a deeper understanding of the complex biological characteristics of mouse cells, MtoZ Biolabs utilizes flow cytometry-based multi-factor analysis technology to provide an efficient and precise method for simultaneously analyzing multiple cell biomarkers. This technology has shown great potential in various fields such as immunology, oncology, and stem cell research.

• • Determining Protein Content in E. coli via Amino Acid Analysis

  In the field of microbiology and biotechnology, Escherichia coli, as an important model organism and industrial production microbe, accurate measurement of its protein content is of great significance for basic research and industrial applications. MtoZ Biolabs provides efficient and reliable technical means for the precise determination of protein content in Escherichia coli using advanced amino acid analysis.

• • Identifying Protein Phosphorylation Sites via Mass Spectrometry

  In mass spectrometry analysis, proteins or peptide segments are ionized into charged particles and then separated through a mass spectrometer. The mass spectrum displays the relationship between the mass-to-charge ratio (m/z) of these particles and their intensity (signal size). Interpreting the mass spectrum requires understanding the fragmentation patterns of peptide segments and the mass changes caused by phosphorylation.

• • Steps for Protein Determination Using Circular Dichroism

  Circular Dichroism (CD) is a spectroscopic technique based on electromagnetic waves that can analyze the structural features of proteins by measuring the difference in absorption of left and right circularly polarized light. It is currently widely used in determining the secondary structure of proteins, and is a fast, simple, and relatively accurate method for studying the conformation of proteins in dilute solutions.