Resources

Proteomics Databases



Metabolomics Databases

• • Lipidomics MALDI Imaging of Escherichia Coli

  Escherichia coli (E. coli) is a common bacterium widely distributed in nature and belongs to Gram-negative bacteria. In the fields of modern microbiology and biotechnology, precise analysis of the lipid composition of E. coli is particularly important. MALDI imaging technology combines the high sensitivity of MALDI mass spectrometry with the spatial resolution of imaging technology, which can directly observe and analyze the distribution of lipid molecules at the cellular and even tissue levels.

• • Molecular Weight and Isoelectric Point Analysis of Proteins

  Molecular Weight Analysis 1. SDS-PAGE (Sodium Dodecyl Sulfate-PolyAcrylamide Gel Electrophoresis): SDS-PAGE is a commonly used method for determining protein molecular weight. By conducting electrophoresis in a gel containing SDS (sodium dodecyl sulfate), proteins separate according to their molecular weight. After electrophoresis, proteins can be visualized through staining, and by comparison with standard proteins of known molecular weight, the molecular weight of sample proteins can be estimated.

• • Peptide Circular Dichroism Spectroscopy

  Peptide Circular Dichroism (CD) is a powerful spectroscopic technique primarily used for studying the secondary structure of peptides and proteins. It is based on a simple principle: when optically active substances such as peptides absorb circularly polarized light, specific spectral signals are generated. These signals can reveal structural features of proteins and peptides, such as α-helices, β-folded structures, and random coil structures.

• • Organic Acids in Cardiac Tissue

  The analysis of organic acids in cardiac tissue is crucial in the study of cardiac physiology and pathology. Organic acids are not only key intermediates in cardiac metabolism, but also play important roles in regulating energy supply, pH balance, and electrolyte balance in cardiac muscle cells. Therefore, a detailed analysis of organic acids in cardiac tissue is of great value in understanding cardiac function, diagnosing cardiac diseases, and developing new treatment strategies.

• • 4D Label-Free Proteomics Technology and Applications

  4D label-free proteomics is an advanced protein analysis method that combines Data Independent Acquisition (DIA) and label-free quantification strategies. This technique allows for the systematic analysis of protein expression changes in biological samples without the use of chemical labels. Due to its efficiency and accuracy, 4D label-free proteomics has widespread applications in biomedical research, biomarker identification, and drug development.

• • Amino Acids and Their Derivatives in Liver Tissues

  The liver, as one of the most important metabolic organs in the human body, plays various physiological functions, including but not limited to metabolism, detoxification, and protein synthesis. In these processes, amino acids and their derivatives play crucial roles. MtoZ Biolabs utilizes advanced mass spectrometry technology to explore the mysteries of amino acids and their derivatives in the liver for medical research and clinical applications.

• • Live Cell Protein Interaction Thermal Stability Detection

  Cellular protein-protein interaction and thermal stability assay is an experimental method used to study the interactions between proteins and their stability under different temperature conditions. This technique is particularly important in biomedical research as it helps understand the functions of proteins and their roles in diseases. The detailed steps of this technique are as follows.

• • Relative Quantification of Protein Phosphorylation Level

  In the field of cell biology, research on protein phosphorylation occupies an important position. Protein phosphorylation is one of the most common and functionally significant post-translational modifications in biology. It plays important roles in various biological processes, including cell division, growth, death, and signal transduction.

• • Differential Analysis of Proteome

  Proteomics is a discipline that studies all proteins and their interactions within an organism. Differential analysis of the proteome is an important branch of proteomics, aiming to compare protein expression differences between different biological samples to reveal biological processes and disease mechanisms.

• • Microproteomics Analysis Technology

  Microproteomics analysis is a method focused on the detection and analysis of trace protein samples. This technique is typically applied in situations where sample quantity is scarce or protein content is low, such as single cells, microbial samples, and clinical specimens.