Resources
Proteomics Databases
Metabolomics Databases
-
• High Throughput Screening of Drugs
High throughput screening of drugs is a methodology that leverages automated technologies and large-scale assay systems to rapidly evaluate the interactions between thousands of compounds and biological targets within a short time. It represents a critical step in modern drug discovery pipelines. Through high throughput screening, researchers can efficiently identify candidate molecules with biological activity against specific targets from vast compound libraries. This technology significantly improv......
-
• Proteomics of Spatially Identified Tissues in Whole Organs
Proteomics of spatially identified tissues in whole organs is an emerging paradigm in high-resolution, high-throughput proteomics that integrates conventional protein analysis techniques with spatial information acquisition. Its goal is to reveal the spatial distribution patterns, expression states, and functional heterogeneity of proteins at the scale of intact organs. While traditional proteomics can identify thousands of proteins within a sample, it typically relies on homogenized tissue extracts a......
-
• High Content Screening Assay
High content screening assay is an advanced drug discovery strategy that integrates cellular imaging technologies with automated data analysis. Unlike traditional screening methods that rely on single endpoints—such as cell viability or enzyme activity—this approach captures large volumes of data at the cellular level, including morphological features, multiparametric fluorescence signals, and subcellular structures. This enables multidimensional characterization of compound effects, providing more co......
-
Cancer proteomics is a systematic scientific discipline that focuses on investigating the composition, expression levels, post-translational modifications, and functional networks of proteins associated with cancer. As a specialized branch of proteomics applied in oncology, cancer proteomics utilizes high-throughput mass spectrometry and bioinformatics approaches to comprehensively analyze the dynamic changes in protein profiles across various samples, including tumor tissues, blood, and cell lines. I......
-
Single B cell sequencing is a specialized technology used to analyze the genomic information of individual B cells. B cells are a crucial component of the immune system, responsible for producing antibodies and protecting the body against infection by recognizing and neutralizing foreign pathogens. This technology enables researchers to deeply explore the gene expression profiles and somatic mutations of individual B cells, thereby revealing their specific roles in immune responses. Single B cell se......
-
The LTQ mass spectrometer is a high-sensitivity, high-resolution analytical instrument widely used in life sciences, drug development, environmental monitoring, and other research and applied fields. In proteomics, metabolomics, and pharmacokinetic studies involving complex biological samples, the LTQ mass spectrometer has become an indispensable tool for molecular-level investigations due to its excellent capabilities in multistage tandem mass spectrometry (MSⁿ), fast scan speed, and efficient ion tr......
-
• Single Cell Combinatorial Indexing RNA Sequencing
Single cell combinatorial indexing RNA sequencing is a high-throughput sequencing technology capable of capturing and analyzing the entire RNA content within individual cells. This technique plays a pivotal role in dissecting cellular diversity and functional states within complex biological systems. In fundamental biological research, single cell combinatorial indexing RNA sequencing has been widely applied to investigate the basic mechanisms underlying cell development, differentiation, and function......
-
• Single Cell Bacterial Sequencing
Single cell bacterial sequencing refers to a cutting-edge technique that enables direct genomic or transcriptomic analysis of individual bacterial cells without relying on population-averaged signals. Unlike traditional bacterial sequencing methods, this approach uncovers genetic variations, functional differences, and environmental response characteristics at the single-cell level, significantly advancing research in microbial ecology, pathogenesis, and antibiotic resistance mechanisms. The advent of......
-
• Metabolite Set Enrichment Analysis
Metabolite set enrichment analysis is a powerful technique aimed at elucidating the metabolic states of organisms by identifying and assessing changes in metabolites present in biological samples. Metabolites, which are the intermediate or final products of chemical reactions within organisms, undergo concentration changes that reflect the metabolic activities of cells, tissues, and entire organisms under varying physiological and pathological conditions. By systematically examining these metabolite c......
-
• X-Ray Crystallography in Protein Analysis
X-ray crystallography in protein analysis is a classical structural biology technique based on the principle of X-ray diffraction, widely used to determine the three-dimensional structures of proteins. Since its development in the mid-20th century, this technique has profoundly advanced our understanding of the conformational characteristics and functional mechanisms of biomolecules. It has also served as a cornerstone in driving breakthroughs in modern biochemistry, molecular biology, and rational dr......
How to order?
