Resources

Proteomics Databases



Metabolomics Databases

• • What Data Does Circular Dichroism Primarily Measure?

  Circular Dichroism (CD) spectroscopy, also known as circular dichroism spectroscopy, is a spectral technique used to analyze chiral compounds, particularly the structure and dynamics of biomolecules such as proteins and nucleic acids. CD spectroscopy provides information about molecular structure (such as protein secondary structure), conformational changes, and intermolecular interactions.

• • Amino Acid Determination: Precise Content Analysis

  Amino acid determination has important applications in many biochemical and biomedical research. For example, it can be used to determine the amino acid composition of proteins, helping researchers understand the structure and function of proteins. In addition, amino acid determination can also be used to monitor the levels of amino acids in biological samples, which is crucial for studying the pathogenesis and treatment effects of various diseases.

• • Amino Acid Composition Detection: Revealing the Biological Code

  The DNA in the organism is the foundation of life, containing genetic information. However, DNA does not directly participate in the process of protein synthesis in the organism, but is transformed into proteins through the processes of transcription and translation. In the process of protein synthesis, amino acids play an important role. Amino acids are the basic units that make up proteins, and different combinations of amino acids form different proteins, which is called the genetic code.

• • The Best Dilution Strategy for HCP Detection

  HCP (Host Cell Protein) is a protein impurity that may remain in the production process of biopharmaceuticals, originating from the host cells used for producing these drugs. The presence of HCP can potentially impact the safety, efficacy, and quality of the drugs, therefore requiring strict detection and control. Different HCP detection methods have varying sensitivities and specificities, thus the optimal dilution strategy may differ.

• • Antibody Drug Microflow Imaging Particle Analysis

  Antibody drugs are a class of biopharmaceuticals that utilize the immune system's mechanism of specific recognition and binding to specific targets in the body. They are widely used in the treatment of various diseases, such as cancer, autoimmune diseases, and infectious diseases. Due to their importance in clinical therapy, ensuring the quality, purity, activity, and safety of antibody drugs is crucial.

• • Analysis of Recombinant Protein Drugs with FcyRI/FcyRII/FcyRIII Interactions

  Recombinant protein drugs are protein products derived from animals and plants through biotechnological research and development, which possess certain biological activities and can prevent and treat human, animal, and plant diseases. Compared to small molecule drugs, recombinant protein drugs have advantages such as high activity, high specificity, and low toxicity, making them favored by researchers.

• • Analysis of Components of Antibody Drug Culture Medium

  Antibody drugs are a class of drugs that are artificially synthesized antibodies used to treat diseases by specifically binding to target molecules. Common types of antibody drugs include monoclonal antibodies, artificially synthesized antibody fragments, immunotoxins, and antibody drug conjugates. Antibody drugs have shown significant efficacy in treating various diseases, such as cancer, autoimmune diseases, inflammatory diseases, immunoregulation, and ophthalmic diseases.

• • Advantages and Disadvantages of Protein Complex Identification using MALDI-TOF-MS and ESI-MS

  Mass spectrometry (MS) is a powerful analytical tool that plays a crucial role in identifying and characterizing protein complexes. Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF-MS) and Electrospray Ionization Mass Spectrometry (ESI-MS) are two commonly used MS techniques.

• • Mechanism of Protein Identification Using Shotgun Proteomics

  Shotgun proteomics is a powerful and high-throughput technique for the comprehensive analysis and identification of proteins in complex biological samples. This approach leverages mass spectrometry (MS) to analyze peptides derived from protein digestion, providing detailed insights into the proteome.

• • Principle of Membrane Protein Identification

  Membrane proteins are crucial components of cellular function, playing vital roles in processes such as signaling, transport, and cellular communication. Identifying and characterizing these proteins is essential for understanding their functions and the mechanisms of various diseases.