Resources

Proteomics Databases



Metabolomics Databases

• • Exploring Biological Structures: Circular Dichroism Experiment

  Circular Dichroism (CD) is a spectroscopic technique widely used in the study of the structure of biomacromolecules, particularly proteins and nucleic acids.

• • Circular Dichroism Spectroscopy Analysis of Protein Secondary Structure

  Circular dichroism (CD) spectroscopy is a widely used method for studying the secondary structure and its changes of proteins. By analyzing the CD spectrum of a protein, the approximate composition and distribution of its secondary structure can be obtained.

• • Application of Unknown Proteins Sequencing

  Proteins are among the most diverse and complex molecules in living organisms, participating in almost all life processes. As proteomics advances, studying unknown proteins has become a major area of life science research. Unknown Protein Sequencing (UPS) is a method used to identify and analyze unknown proteins, helping to understand the basic functions of organisms and having broad applications in disease diagnosis, drug development, and biotechnology.

• • Workflow of Unknown Proteins Sequencing

  Proteins are essential molecules in living organisms, fulfilling roles in structure, catalysis, signaling, and more. To fully understand the functions of proteins and their roles in biological processes, protein sequence analysis is a crucial step.

• • Principle of Unknown Proteins Sequencing

  Proteins are essential molecules in living organisms that perform a wide range of functions. They are composed of chains of amino acids and exhibit highly complex three-dimensional structures. The function of a protein is determined by its specific amino acid sequence and spatial conformation.

• • Workflow of Peptide Mass Fingerprinting

  Peptide mass fingerprinting (PMF) has become an essential technique in the field of proteomics, providing a reliable method for protein identification. The process involves the enzymatic digestion of proteins into peptides, mass spectrometric analysis of these peptides, and the subsequent comparison of the resulting mass spectra to theoretical spectra in protein databases.

• • Principle of Peptide Mass Fingerprinting

  Peptide mass fingerprinting (PMF) has emerged as a powerful technique in proteomics, enabling researchers to identify proteins with high precision and efficiency. This method leverages mass spectrometry to analyze peptide masses derived from protein digests, providing a unique "fingerprint" that can be matched against protein databases.

• • Mechanism of Membrane Protein Identification

  Membrane proteins play critical roles in numerous cellular functions, including signaling, transport, and communication. Understanding their mechanisms and identifying these proteins is essential for advancing biomedical research and therapeutic development. However, the study of membrane proteins is fraught with challenges due to their hydrophobic nature and low abundance.

• • Application of Membrane Protein Identification

  Membrane proteins are pivotal to numerous cellular functions, including signal transduction, transport, and cell communication. Understanding and identifying these proteins is crucial for advancing biomedical research and developing new therapeutic strategies.

• • Workflow of Membrane Protein Identification

  Membrane proteins play critical roles in various cellular processes, including signal transduction, transport, and cell-cell communication. Identifying and characterizing these proteins is crucial for understanding their functions and their implications in health and disease. However, membrane proteins present unique challenges due to their hydrophobic nature and low abundance.