Lipidome Identification Service
Lipidome Identification Service refers to the systematic characterization of lipid species using advanced analytical methods, particularly mass spectrometry coupled with chromatographic separation. This service enables the identification of hundreds to thousands of lipid species across diverse classes, providing detailed insight into lipid composition, distribution, and functional roles. MtoZ Biolabs offers professional Lipidome Identification Service designed to deliver high-quality and reproducible lipidomic data.
Lipids are a structurally diverse and functionally essential class of biomolecules found in every living organism. They serve as building blocks of cell membranes, energy storage molecules, and signaling mediators, while also influencing protein activity, gene regulation, and immune responses. Disturbances in lipid metabolism are closely linked to major health conditions such as obesity, diabetes, and cardiovascular disease. The complete set of lipids within a cell, tissue, or organism is collectively referred to as the lipidome. Comprehensive identification of the lipidome has become indispensable for understanding cellular processes, discovering disease biomarkers, monitoring therapeutic interventions, and developing novel drugs.
Service at MtoZ Biolabs
At MtoZ Biolabs, we employ optimized extraction protocols tailored to different lipid classes to ensure maximum recovery and integrity of analytes. For complex samples, chromatographic separation methods are applied to isolate lipid groups, which are then characterized by mass spectrometry. Structural information is further refined through MS/MS fragmentation, and results are integrated with curated lipid databases to provide accurate annotation and classification.
The complexity of lipid species requires robust, high-resolution analytical platforms that can resolve subtle structural variations. MtoZ Biolabs is equipped with a comprehensive suite of advanced mass spectrometry platforms. Our facility combines triple quadrupole systems for targeted lipid analysis with high-resolution hybrid Orbitrap instruments for untargeted, in-depth profiling. Together, these instruments provide the resolution and dynamic range necessary to capture both abundant lipid classes and trace-level metabolites with confidence and reproducibility.
Lipid Classes We Identify
Analysis Workflow
Ward, A. V. et al. J Mammary Gland Biol Neoplasia. 2021.
Figure 1. General Workflow of Lipidomics for Breast Cancer Research
Service Advantages
☑️Expertise: Extensive experience in mass spectrometry-based lipidomics and bioinformatics analysis.
☑️Advanced Platforms: Cutting-edge LC-MS/MS systems guaranteeing reliable, fast, and highly accurate analysis service.
☑️Customized Workflows: Tailored solutions designed to match client-specific sample types and research goals.
☑️Quality Assurance: Internal standards and validated protocols guarantee reproducible data.
☑️Comprehensive Support: From experimental design to final data interpretation, MtoZ Biolabs provides end-to-end support.
Sample Submission Suggestions
Storage and Shipping: Samples should be stored at -80℃ and shipped with dry ice
Note: If you have special sample types or require additional guidance, please contact us for personalized support before sample preparation.
Applications
The mass spectrometry-based lipidome identification service provides insights across a wide spectrum of research and industrial fields:
1. Pharmaceuticals and Drug Development
Identification of lipid biomarkers for disease diagnosis, monitoring drug effects on lipid metabolism, and characterizing lipid-based drug delivery systems.
2. Nutrition and Food Science
Analysis of lipid composition in functional foods, oils, and dietary supplements to evaluate quality, stability, and health effects.
3. Agriculture
Characterization of plant lipids involved in stress responses, defense mechanisms, and crop quality improvements.
4. Metabolism and Systems Biology
Mapping lipid metabolic pathways to understand their roles in energy regulation, signaling cascades, and disease mechanisms.
5. Basic Biological Research
Comprehensive profiling of lipidomes in cells, tissues, and model organisms to study membrane biology, cell signaling, and developmental processes.
By revealing the full spectrum of lipids, MtoZ Biolabs empowers discoveries that drive innovation across biology, medicine, and industry. If you are interested in our Lipidome Identification Service, please feel free to contact us.
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