In Vitro Biology Assay Service | Drug Discovery
- Hit-to-lead and lead optimization
- Mechanism of action (MoA) studies
- Toxicity screening and therapeutic index estimation
- Target validation and pathway mapping
- Antibody and biologics functional screening
The relentless pursuit of novel therapeutics faces a formidable challenge: efficiently identifying compounds with genuine pharmacological potential while minimizing costly late-stage failures. In vitro biology assays serve as the indispensable first line of defense in this battle, providing controlled, high-resolution insights into drug-target interactions, cellular responses, and compound efficacy/toxicity long before animal or human testing begins. These assays bridge the gap between biochemical predictions and biological reality, enabling researchers to prioritize lead compounds with higher confidence. MtoZ Biolabs leverages cutting-edge cell-based platforms, high-content screening technologies, and multiplexed detection systems to deliver In Vitro Biology Assay Service that accelerates your drug discovery pipeline from target validation to candidate selection.
Service at MtoZ Biolabs
MtoZ Biolabs' In Vitro Biology Assay Service offers a rapid, scalable, and cost-effective means to evaluate the pharmacological activity, mechanism of action (MOA), toxicity, and therapeutic potential of candidate compounds. Unlike in vivo systems, in vitro assays provide a controlled environment to dissect cellular and molecular responses with high precision, enabling data-rich insights before entering animal studies or clinical development. These assays are essential for hit validation, lead optimization, target deconvolution, and early safety assessments.
We employ state-of-the-art technologies including high-content imaging, flow cytometry, luminescence/fluorescence-based detection, and ELISA to quantify functional endpoints such as proliferation, cytotoxicity, apoptosis, receptor activation, and biomarker expression. Our services are designed to provide mechanistic clarity and data reproducibility to drive informed decision-making at each stage of your drug discovery program.
We provide a full suite of in vitro assay platforms tailored for different stages of drug discovery:
💠Cell-Based Functional Assays
We offer both 2D and 3D cellular systems using human or animal cell lines, stem cells, or primary cells. Assays include: cell viability and proliferation assays, apoptosis and necrosis assays, and reporter gene assays
💠Target-Based Biochemical Assays
Designed to study direct drug-target interactions in a purified system. Services include: enzyme activity and inhibition assays, receptor-ligand binding assays, ion channel and transporter assays.
💠Biomarker Detection and Quantification
We use ELISA, multiplex immunoassays, and qPCR to evaluate cytokine levels, stress response proteins, and disease-relevant biomarkers. Western blot or capillary immunoassays are used for protein-level validation.
💠High-Content Imaging and Phenotypic Screening
Automated imaging and AI-assisted analysis allow for high-throughput, multiparametric evaluation of cellular phenotypes, subcellular localization, or compound-induced morphological changes.
💠Custom Assay Development
Tailored assay design using gene editing (CRISPR/Cas9), overexpression/knockdown systems, and co-culture models to mimic disease-specific microenvironments.
Service Advantages
☑️Tailored Experimental Design
Each project is customized to match the biological context of your target and therapeutic modality, ensuring biologically relevant and translatable results.
☑️Experienced Scientific Team
Our scientists possess extensive expertise in pharmacology, molecular biology, and assay development, providing hands-on support from study design to data interpretation.
☑️Advanced Analysis Platform
MtoZ Biolabs established an advanced In Vitro Biology Assay Service platform, guaranteeing reliable, fast, and highly accurate analysis service.
☑️One-Time-Charge
Our pricing is transparent, no hidden fees or additional costs.
Applications
In vitro biology assays at MtoZ Biolabs can support a wide range of applications:
These assays can be applied to small molecules, peptides, antibodies, nucleic acid-based therapeutics, and PROTACs across therapeutic areas such as oncology, immunology, neurology, and metabolic disorders.
Deliverables
1. Comprehensive experimental details (materials, instruments, and methods)
2. High-quality raw data and processed data
3. Graphical visualization of assay outcomes
4. Statistical interpretation and biological insights
5. A comprehensive technical report with conclusions and recommendations
Unlock the full potential of your drug discovery program with MtoZ Biolabs' In Vitro Biology Assay Service. Contact us today to discuss your project needs or request a customized proposal.
Related Services
Lead Optimization Service | Drug Discovery
Hit-to-Lead Identification Service | Drug Discovery
Hit Identification Service | Drug Discovery
Target Identification and Validation Service| Drug Discovery
How to order?
