Immune Peptide Library Screening Service

Immune peptide library screening is a technique based on large-scale peptide library screening, specifically used to identify peptides related to the immune system, especially those that bind to immune receptors. By constructing a diverse peptide library and combining high-throughput screening with mass spectrometry, this method efficiently identifies potential epitope peptides in the immune system and evaluates their immunogenicity. This service provides an important experimental tool for researching immune recognition, antigen presentation, and vaccine design.

 

Immune peptide library screening service is widely applied in immunology research, tumor immunology, vaccine development, and infection immunology. By screening peptides that bind to immune receptors, researchers can discover new immune epitopes, assess the immunogenic potential of peptides, and provide data support for vaccine development, immunotherapies, and personalized immune treatments.

 

Services at MtoZ Biolabs

Based on high-resolution mass spectrometry platforms combined with high-throughput screening technology, MtoZ Biolabs offers the immune peptide library screening service focusing on screening immune-related peptides that bind to immune receptors. This service constructs a diverse peptide library and analyzes the binding affinity and immunogenicity of peptides with immune receptors. Clients can obtain peptide sequence information, binding affinity, immunogenicity assessments, and data related to immune responses, facilitating further research discoveries. The services we offer include, but are not limited to, the following:

 

1. Library Design and Construction

Based on research needs, a diverse immune peptide library is designed and constructed to ensure broad coverage of immune-related peptides, providing a solid foundation for effective screening.

 

2. High-Throughput Screening

High-throughput screening technology is used to rapidly screen peptides in the library through an automated platform, identifying candidate peptides that bind to immune receptors (such as TCR or antibodies).

 

3. Functional Peptide Characterization

Functional peptides that are selected are subjected to qualitative and quantitative analysis to evaluate their immunogenicity, affinity, and biological activity, determining their potential role in immune responses.

 

4. Peptide-Protein Binding Assay

Peptide-protein binding assays are performed to verify the binding characteristics of the selected peptides with immune receptors, providing data support for immunotherapy or vaccine design.

 

5. Peptide Synthesis

Based on the selected peptide sequences, peptides are synthesized and provided for subsequent functional validation and immune research.

 

Analysis Workflow

1. Library Design and Construction

Based on the client's needs, research objectives are defined, and a library covering a wide range of immune-related peptides is designed and constructed.

 

2. High-Throughput Screening

Using advanced high-throughput screening technology and an automated platform, peptides in the library are quickly screened to identify those with high affinity for immune receptors.

 

3. Screening Result Analysis

The selected candidate peptides are thoroughly analyzed to assess their immunogenicity, binding characteristics, and potential biological functions, providing a foundation for further research.

 

4. Binding Assay Validation

Selected immune peptides undergo additional binding assays to confirm their specificity and efficacy with immune receptors, ensuring the reliability of the screening results.

 

Service Advantages

1. Efficient Screening Capability

Using high-throughput screening technology, peptides binding to immune receptors are quickly selected from the peptide library, significantly improving research efficiency.

 

2. Diverse Data Analysis

Provides comprehensive data analysis services, including peptide immunogenicity assessment, epitope prediction, and functional annotation, offering strong data support for immune research and vaccine development.

 

3. Customized Services

Peptide libraries are designed and constructed based on the client's research needs, addressing the diverse requirements of various immune-related studies.

 

4. Reliable Experimental Results

Through immunoaffinity purification and peptide-protein binding assays, we ensure that selected peptides exhibit high specificity and biological efficacy, providing reliable data support.

 

Applications

1. Tumor Immunity Target Discovery

The immune peptide library screening service can be used to screen peptides bound to immune receptors in tumor tissues, identifying potential neoantigens and providing data support for the development of tumor immunotherapy targets.

 

2. Vaccine Epitope Design

By screening peptides with high affinity to immune receptors, this service helps design more immunogenic vaccine epitopes, enhancing vaccine efficacy.

 

3. Immune Response Research

The immune peptide library screening service can be used to screen and identify immune peptides, revealing T cell and B cell immune response mechanisms, providing data support for personalized immunotherapy.

 

4. Immune Monitoring and Neoantigen Screening

Combining immune peptide library screening technology, it is widely applied in pathogen infection research, immune evasion mechanisms, and neoantigen identification, providing essential data for immune monitoring.

 

FAQ

Q1: How Are Peptides Selected in Immune Peptide Library Screening?

A1: We design a diverse peptide library based on the client's research objectives and the type of immune receptor. Then, we use high-throughput screening technology to select peptides with high affinity for immune receptors (such as T cell receptors or antibodies) from the library, further analyzing their immunogenicity.

 

Q2: Does the Service Support Screening of Post-Translationally Modified Peptides?

A2: Yes, we support screening for post-translationally modified peptides, including phosphorylation, acetylation, and others. If needed, please contact us in advance. We will optimize peptide screening and data analysis strategies based on client requirements to ensure the accurate identification of modified peptides.