Xanthan Gum Analysis Service | Pharmaceutical Excipient

Xanthan gum is a high-molecular-weight polysaccharide produced by the fermentation of Xanthomonas campestris. Due to its excellent thickening, emulsifying, and stabilizing properties, it is widely used in the food, cosmetic, and pharmaceutical industries. In drug formulations, xanthan gum functions not only as a binder, suspending agent, and controlled-release material, but also improves drug dissolution, enhances formulation stability, and modulates release rates. With increasingly strict regulatory standards, the quality control of pharmaceutical excipients has become a critical factor in ensuring drug safety and efficacy. Leveraging advanced analytical platforms and an experienced scientific team, MtoZ Biolabs offers a comprehensive xanthan gum analysis service to provide pharmaceutical companies and research institutions with systematic quality evaluation and testing solutions, ensuring compliance and consistency from development to production.

 



Figure 1. The Structure of Xanthan Gum 

 

Services at MtoZ Biolabs

MtoZ Biolabs’ xanthan gum analysis service covers multidimensional quality and structural testing designed to comprehensively evaluate physicochemical properties and application suitability. Our testing items include:

1. Physicochemical Analysis: Determination of loss on drying, ash content, and moisture to ensure compliance with pharmacopeial and industry requirements.

2. Residual Solvent Detection: Using HPLC or GC to quantify methanol, ethanol, isopropanol, and other residual solvents, ensuring excipient purity and safety.

3. Monosaccharide Composition and Structural Analysis: Determination of monosaccharide composition and molecular characteristics by FT-IR, NMR, XRD, and other spectroscopic methods, ensuring structural integrity.

4. Molecular Weight Determination: Molecular weight and distribution analysis using GPC/SEC and mass spectrometry to evaluate stability and controllability in formulations.

5. Microbial Limit Testing: Examination of aerobic bacteria, molds, and yeasts according to pharmacopeial standards to ensure biosafety.

 

Through these multidimensional tests, MtoZ Biolabs provides clients with a complete evaluation of xanthan gum quality, covering the full process from raw material selection to formulation development.

 

Analysis Workflow

1. Sample Receipt and Registration: Numbering and preprocessing of submitted xanthan gum samples.

2. Physicochemical Testing: Measurement of moisture, ash, and other basic parameters.

3. Component and Residual Analysis: Chromatographic and spectroscopic analysis of residual solvents, monosaccharide composition, and structure.

4. Molecular Weight and Microbial Testing: Standardized molecular weight determination and microbial limit testing.

5. Data Compilation and Report Generation: Delivering complete datasets, spectra, and comprehensive analytical conclusions.

 

Service Advantages

1. Comprehensive Testing Dimensions

Our xanthan gum analysis service covers physicochemical properties, composition, residual solvent detection, molecular weight distribution, and microbial safety, ensuring clients receive a full-spectrum quality evaluation of excipients.

 

2. Standardized and Compliant Methods

All tests follow international pharmacopeial and industry standards, guaranteeing authoritative and comparable results that support drug R&D and regulatory submissions.

 

3. Flexible and Customized Solutions

We provide tailored testing combinations based on different R\&D requirements and application scenarios, enabling clients to efficiently resolve excipient quality challenges.

 

4. Advanced Analytical Platforms

Our xanthan gum analysis service relies on HPLC, GC, NMR, XRD, and microbial detection systems, ensuring accuracy, reliability, and reproducibility of results.

 

5. Professional Data Interpretation

Beyond providing experimental results, we offer contextual interpretation and trend analysis, helping clients optimize formulations and understand excipient performance in drug products.

 

Applications

✔️ Drug Development: Evaluation of xanthan gum as a binder or controlled-release carrier.

✔️ Quality Control: Monitoring batch-to-batch consistency and stability to ensure manufacturing reliability.

✔️ Regulatory Submissions: Providing experimental data to support registration and compliance.

✔️ Process Optimization: Assisting in the development of novel formulations and excipient applications.

 

Sample Submission Suggestions

1. At least 10 g of xanthan gum is recommended to complete all testing items.

2. Samples must be sealed and stored dry to prevent moisture absorption or contamination.

3. Provide sample information such as source, batch number, and intended application.

4. For special analytical needs, clients may contact us in advance to design an optimal plan.

 

Deliverables

1. A complete experimental report including methods, procedures, and raw data.

2. Spectra, chromatograms, and related analytical charts.

3. Quantitative results for physicochemical parameters, residual solvents, molecular weight, and microbial limits.

4. Comprehensive conclusions and application recommendations to support R&D and quality management.

 

As a pharmaceutical excipient, xanthan gum plays a crucial role in formulation development and manufacturing. Its quality control directly impacts drug stability and patient safety. With systematic analytical platforms and a professional technical team, MtoZ Biolabs provides a reliable xanthan gum analysis service to support smooth progress in R&D and regulatory compliance. 

If you require comprehensive and accurate testing and evaluation of xanthan gum, MtoZ Biolabs is ready to provide customized solutions tailored to your needs.