Thematic Analysis Service

• • High-throughput Antibody Screening Service

  High-throughput antibody screening is a powerful and efficient strategy for identifying and characterizing antibodies with high specificity, affinity, and functionality. High-throughput antibody screening enables rapid selection of promising candidates for therapeutic development, diagnostic applications, and fundamental research. By leveraging advanced screening technologies, high-throughput antibody screening accelerates the discovery of monoclonal and recombinant antibodies while maintaining...

• • Neoantigen Sequencing Service

  Neoantigen sequencing is a specialized approach designed to identify tumor-specific antigens generated by somatic mutations. Based on the high-resolution mass spectrometry (LC-MS/MS) platform, combined with genome sequencing and bioinformatics analysis processes, MtoZ Biolabs' neoantigen sequencing service can comprehensively analyze the amino acid sequence information of mutated neoantigens in tumor samples.

• • Antibody-Drug Conjugate (ADC) Sequencing Services

  Antibody-drug conjugate (ADC) sequencing is a high-precision characterization technique designed to comprehensively analyze the molecular structure of ADC, including antibody amino acid sequences, conjugation sites, drug-to-antibody ratio (DAR), linker stability, and modification distribution. The antibody-drug conjugate (ADC) sequencing services provided by MtoZ Biolabs ensure high-sensitivity and high-resolution data acquisition.

• • Oligonucleotide Purity Analysis Services

  Oligonucleotide purity analysis is a critical step for precisely determining the purity of synthesized nucleic acids such as DNA, RNA, and siRNA. Impurities can markedly compromise the quality, stability, biological activity, and experimental reproducibility of oligonucleotides. Accurate purity assessment identifies synthetic by-products, degradation fragments, and other contaminants, thus ensuring reliable downstream experiments. Given the widespread applications of oligonucleotides in gene synthesis......

• • AAV Characterization Services

  Adeno-associated virus (AAV) is a core delivery vector in gene therapy. Its non-pathogenic nature, long-term expression capability, and tissue-specific targeting make it an ideal tool for treating rare diseases, genetic disorders, and cancer. However, the safety and efficacy of AAV products highly depend on precise control of critical quality attributes (CQAs), including capsid integrity (empty/full ratio), genome titer, aggregation levels, and residual impurities (host proteins/DNA).

• • Antibody Drug Discovery Service

  Antibody drug discovery refers to the systematic process of identifying, engineering, and optimizing antibodies for therapeutic applications, ultimately aiming to develop more effective treatments for a wide range of diseases. Antibody-based therapeutics have seen remarkable growth in the pharmaceutical market due to their high specificity, fewer side effects, and ability to modulate complex biological pathways.

• • MALDI TOF Bacteria Identification Service

  MALDI TOF bacteria identification is a cutting-edge method for identifying bacteria based on mass spectrometry technology. Accurate identification of bacteria is essential across various fields, including clinical microbiology, food safety, environmental monitoring, and industrial production. Traditional methods for bacterial identification, such as culture-based assays, biochemical testing, or genetic sequencing, are often time-consuming, labor-intensive, and costly.

• • Epitope Mapping Service

  Epitope mapping is a critical technique in immunology and proteomics that identifies the specific regions, or epitopes, on antigens recognized by antibodies. An epitope, also known as an antigenic determinant, is the precise site where an antibody binds to an antigen, triggering an immune response. Epitopes can be broadly classified into two categories: linear (continuous) epitopes, which consist of a sequential amino acid sequence within a protein, and conformational (discontinuous) epitopes...

• • AAV Characterization Service

  Comprehensive AAV Characterization is crucial to meet stringent regulatory requirements and ensure the safety, purity, and efficacy of gene therapy products. Regulatory bodies such as the U.S. Food and Drug Administration and the European Medicines Agency (EMA) mandate thorough documentation of vector composition, potency, purity, and stability before approving AAV-based therapeutics.

• • Peptide Drug Analysis Service

  Peptides are compounds formed by multiple amino acids linked by peptide bonds and can be prepared via recombinant DNA expression, biological extraction, or chemical synthesis. Peptides represent a unique class of drugs with certain characteristics of small molecule drugs as well as properties of large proteins and other biologics. Most intrinsic signaling molecules are peptide-based, such as enzymes, hormones, and immune response mediators. Over 7,000 natural peptides have been identified.