Resources

Proteomics Databases



Metabolomics Databases

• • Overview of Label-Free Proteomics Experimental Workflow

  Label-free proteomics is a method for analyzing protein expression without the need for pre-labeling samples. The advantages of this method include its simplicity, cost-effectiveness, and applicability to a wide range of sample types.

• • Dia Proteomics

  DIA (Data-Independent Acquisition Proteomics) proteomics is an advanced mass spectrometry technique used for in-depth protein analysis. Compared to the traditional Data-Dependent Acquisition (DDA) method, DIA technology provides higher coverage and quantification accuracy in proteomic research, allowing researchers to analyze proteins in samples more comprehensively. The core of DIA proteomics lies in its mass spectrometry acquisition mode.

• • N-Terminal Protein Sequencing Methods and Applications Overview

  N-terminal protein sequencing is a method used to determine the amino acid sequence at the beginning of a protein or peptide chain. Accurate amino acid sequence information is essential for studying protein structure and function.

• • N-Terminal Amino Acid Sequencing and Edman Degradation Overview

  N-terminal sequencing of amino acids is a technique used to determine the sequence of several amino acid residues at the N-terminal (amino end) of a protein or peptide. This method is particularly important in protein identification and characterization, especially in biochemical and molecular biology research. Edman degradation is the most commonly used method for N-terminal sequencing of amino acids.

• • Generalized Proteomics SILAC

  Ubiquitin proteomics and its SILAC methodUbiquitin proteomics is an important part of the relevant research field, and its role in biology, pathology, pharmacology, and other aspects is increasingly prominent. This article will provide a detailed introduction to ubiquitin proteomics, focusing on the application of Stable Isotope Labeling by Amino acids in Cell culture (SILAC) technology.

• • Plant SUMOylation

  SUMOylation is an important protein post-translational modification process in plants, playing a key role in regulating plant growth, development, and response to environmental stress. SUMO (Small Ubiquitin-like Modifier) is a small protein that affects the function of target proteins by covalently binding to them.

• • Quantification of Free Thiol in Nasopharyngeal Carcinoma Tissue

  In cancer research, in-depth analysis of tumor tissues is crucial. Nasopharyngeal carcinoma, as a common malignant tumor in the head and neck region, requires more precise biomarkers for diagnosis and treatment. MtoZ Biolabs is dedicated to providing important technical support for the study of nasopharyngeal carcinoma tissues using advanced free thiol quantification analysis methods.

• • Redox Proteomics

  Oxidation-reduction modification proteomics is an emerging scientific field that focuses on studying the impact of protein oxidation-reduction modifications on cellular function. This research area combines techniques from chemistry, biology, and proteomics to provide a new perspective on understanding cellular signal transduction, metabolic regulation, and disease mechanisms. The oxidative-reductive state of proteins directly affects their function and interactions within cells.

• • Application of TMT and iTRAQ in Proteomics Research

  TMT (Tandem Mass Tag) and iTRAQ (Isobaric Tags for Relative and Absolute Quantitation) are two commonly used mass spectrometry labeling techniques in proteomics. These techniques are used for quantitative analysis of protein expression levels in different samples and are particularly suitable for comparing the protein composition of biological samples under different conditions, such as healthy and diseased states, or different biological treatments.

• • The Application of TMT Technology in Proteomics

  The Tandem Mass Tag (TMT) quantification technology has a wide range of applications in proteomics. This technique allows researchers to simultaneously quantify proteins in multiple samples using chemically labeled tags. Here are some key examples of the applications of TMT technology: Biomarker discovery: In disease research, TMT technology is used to identify and validate potential biomarkers.