Resources

Proteomics Databases



Metabolomics Databases

• • IP and Co-IP Techniques: Key Steps to Unravel Protein Interaction Networks

  Proteins are one of the most important molecules in cells, playing various functions within the cell. The interactions between proteins form the basis of many biological processes inside the cell. Therefore, understanding the protein-protein interactions is crucial. Among them, Immunoprecipitation (IP) and Co-Immunoprecipitation (Co-IP) are important techniques for analyzing protein interactions.

• • Label-Free Quantitative Proteomics: A Comprehensive Insight of Label-Free Technology

  Introduction Proteins are one of the most important functional molecules in organisms, and studying the expression levels and variations of proteins is crucial for understanding biological processes and disease mechanisms. Over the past few decades, scientists have developed many proteomic techniques, one of which is label-free quantitative proteomics, also known as label-free technology.

• • Comparing IP and MS Methods: In-Depth Analysis of Proteomics Samples

  Proteomics is a discipline that studies the types, quantities, structures, and functions of proteins in biological organisms. In proteomics research, protein enrichment and analysis are often required. Among them, immunoprecipitation (IP) and mass spectrometry (MS) are two commonly used methods.

• • Advantages of Label-Free Proteomics Analysis

  Proteins are important functional molecules in organisms, and studying protein composition and expression levels is crucial for understanding physiological and pathological processes. The development of proteomics technologies has provided us with a comprehensive means to understand protein composition and function. Among them, label-free proteomics analysis has many advantages.

• • Revealing Efficient Experimental Steps for Protein Secondary Structure Analysis

  Proteins are one of the most important molecules in living organisms, playing a crucial role in cell functions and biological processes. Understanding the structure of proteins is of great significance for uncovering their functions and developing drugs. The secondary structure of proteins refers to the local structures formed by hydrogen bond interactions between amino acid residues, including α-helices, β-sheets, and random coils.

• • Decoding Proteomics: A Dive into Label-Free Technology

  Introduction Proteins are one of the most important functional molecules in biological organisms. Studying the composition and function of proteins is of vital importance to understanding the biological processes of life. Proteomics, as a discipline studying the composition and function of proteins, has become a hot field in biomedical research.

• • Detection of Biomolecules Using PCT-DIA Proteomics

  Proteomics is a pivotal technology in biological research, aimed at comprehensively analyzing the composition, structure, and dynamic alterations of the entire proteome in biological samples. In recent years, proteomics based on Data Independent Acquisition (DIA) has made significant strides, particularly when integrated with Pressure Cycling Technology (PCT), leading to notable improvements in detection sensitivity and throughput.

• • Comparative Analysis of Protein Abundance Using iTRAQ, TMT, and SILAC

  Protein abundance comparative analysis is a critical technique in proteomics research, enabling scientists to understand protein expression levels and their dynamic changes across different conditions. Among the commonly used methods, iTRAQ (Isobaric Tags for Relative and Absolute Quantification), TMT (Tandem Mass Tags), and SILAC (Stable Isotope Labeling by Amino acids in Cell culture) are prominent for their respective advantages and specific applications.

• • New Technologies Drive Expansion in Protein Secondary Structure Analysis

  Protein is an essential molecule in living organisms, and its function is closely related to its structure. The structure of proteins can be divided into four levels, with secondary structure referring to the local spatial arrangement of amino acid residues in proteins. Accurate determination of protein secondary structure is of great significance for understanding protein function and properties.

• • Bioinformatics Analysis of DIA-PRM Proteomics Data

  The rapid advancement of proteomics technology has significantly propelled life sciences research. Proteomics, by analyzing the composition and function of proteins in biological samples, provides essential tools for understanding the dynamics of biological systems. Among these technologies, the combination of Data Independent Acquisition (DIA) and Parallel Reaction Monitoring (PRM) has opened new opportunities for large-scale protein quantification analysis.