Resources

Proteomics Databases



Metabolomics Databases

• • How to Select the Best Protocol for IP-MS Analysis?

  Protein-protein interactions are a crucial mechanism for cellular regulation, playing a key role in the cellular processes and the development of diseases. Immunoprecipitation-mass spectrometry (IP-MS) analysis is a highly sensitive and efficient technique that helps scientists reveal protein-protein interaction networks.

• • How to Analyze Protein-Peptide Interactions Using IP-MS?

  With the continuous development of biopharmaceuticals, the study of protein-protein interactions has become a key to exploring biological activities within organisms. In the study of protein-protein interactions, immunoprecipitation followed by mass spectrometry (IP-MS) has become an important tool that can help us decipher the nature of protein-peptide interactions.

• • Membrane Proteomics Exploring Hidden Functions and Interactions in the Cell Membrane

  The cell membrane is a barrier that separates the internal and external environments of the cell. It not only maintains the integrity of the cell structure but also plays crucial roles in many biological processes. In addition to its traditional structure and functions, the cell membrane also harbors numerous hidden functions and interactions that are vital for cellular regulation and communication.

• • How to Use Label-Free Quantitative Proteomics to Reveal Molecular Mechanisms?

  Proteomics is an important technique in contemporary biomedical field which helps us to gain deeper insights into the complex molecular mechanisms within cells and organisms. Unlabeled quantitative proteomics is a key technology in proteomics, which allows for the quantitative analysis of protein abundance and expression levels, revealing the molecular mechanisms of biological processes and providing valuable information for biopharmaceutical development and disease treatment.

• • How Does Exosome Proteomics Identify Differentially Expressed Exosomal Proteins?

  Extracellular vesicles are a type of small membrane vesicles secreted by cells, containing abundant proteins, nucleic acids, and bioactive molecules. In recent years, the study of proteomics of extracellular vesicles has gained widespread attention.

• • Decoding the Relationship Between Glycosylation and Immune Function

  Glycosylation of antibodies refers to the carbohydrate-related modification process on antibody molecules. Glycosylation is an important regulatory factor for protein structure and function, particularly crucial for biotherapeutic antibodies in the field of proteomics.

• • How Does Glycomics Achieve Comprehensive Analysis and Quantification of Glycometabolism?

  Glycomics is a discipline that studies the structure and function of all sugar molecules in cells, tissues, or organisms. Similar to proteomics and genomics, glycomics plays an important role in the field of biopharmaceutical protein research. The structural diversity and widespread distribution of sugar molecules make a comprehensive analysis of glycolysis challenging, but the continuous development of glycomics analysis provides effective solutions for this goal.

• • How to Analyze Peptide Structures in Complex Samples Using Cross-Linking Mass Spectrometry?

  Peptide drugs are highly regarded in the field of biopharmaceuticals due to their high efficacy and lower toxicity. However, the complex structure of peptides makes it crucial to have a comprehensive understanding of their properties and functions. Cross-linking mass spectrometry (XL-MS) technology has emerged as a powerful tool that provides valuable insights into the mysteries of peptide structures in complex samples.

• • Protein Mass Spectrometry Analysis of Interacting Protein Samples

  In the field of biopharmaceuticals, protein-protein interactions are the basis of many biological processes and also play an important role in drug development. In order to gain a deeper understanding of the function and regulation mechanisms of interacting proteins, scientists employ protein mass spectrometry analysis, which is a powerful tool that helps us comprehensively analyze interacting protein samples and thus drive the development of the biopharmaceutical field.

• • MRM-Based Analysis of Targeted Proteomics

  Targeted proteomics is a highly specific and sensitive method for quantitative protein analysis, widely applied in biomarker validation, disease research, and drug development. Multiple Reaction Monitoring (MRM) is one of the most commonly used methods in targeted proteomics. MRM analysis relies on mass spectrometry to selectively monitor precursor ions and their fragment ions of specific peptides, achieving high sensitivity and precision in quantifying target proteins.