Milk Peptidomics Analysis Service
Milk peptidomics refers to the comprehensive identification, quantitative analysis, and functional prediction of endogenous short peptides in milk samples using mass spectrometry and other high-throughput techniques. Compared to traditional protein analysis, peptidomics focuses on low-molecular-weight peptides with well-defined biological functions, offering greater sensitivity in revealing the nutritional activity of milk and the impact of processing procedures.
As a CRO specializing in multi-omics research, MtoZ Biolabs offers a one-stop Milk Peptidomics Analysis Service that integrates sample processing and data interpretation. Leveraging high-resolution mass spectrometry systems such as the Orbitrap Fusion Lumos and Q Exactive HF, we support both academic and industrial clients in mining bioactive peptides from dairy sources, advancing research in nutritional science, food safety, and the development of functional dairy products.
Services at MtoZ Biolabs
MtoZ Biolabs’ Milk Peptidomics Analysis Service combines acidic extraction, molecular weight cutoff filtration, and reversed-phase solid-phase extraction for multi-dimensional sample preparation. High-resolution LC-MS/MS platforms enable comprehensive detection and quantification of natural milk peptides and their derivatives. Our service covers various functional peptide categories including casein-derived peptides, antimicrobial peptides, immunomodulatory peptides, heat-stress peptides, breed-specific marker peptides, and post-translationally modified peptides. Deliverables include peptide profiling, differential expression analysis, functional annotation, and multi-dimensional visualization. Additionally, integrated multi-omics analyses combining proteomics and metabolomics data are available upon request.
Analysis Workflow
Services Advantages
1. Optimized Extraction Protocols
MtoZ Biolabs has developed specialized peptide extraction protocols tailored for various milk matrices such as skim milk, whey powder, and fermented dairy products. These methods effectively remove high-molecular-weight proteins and lipid contaminants, improving peptide recovery and detection coverage.
2. High-Resolution Instrumentation
Our Milk Peptidomics Analysis Service employs Thermo Q Exactive HF and Orbitrap Fusion Lumos mass spectrometers, paired with nano-LC systems. This configuration ensures high-precision and reproducible peptide identification, particularly suitable for detecting low-abundance peptides in complex natural matrices.
3. Flexible and Customized Solutions
We offer tailored workflows based on the client’s research goals, sample types, and experimental conditions. From sample pretreatment and MS parameter configuration to target peptide selection and annotation depth, our modules are adaptable. Whether verifying specific bioactive peptides or comparing processing effects across different dairy products or animal breeds, we provide directed and scalable analysis solutions aligned with practical research or product development needs.
4. Transparent Pricing
We adhere to standardized workflows with clearly itemized quotes and no hidden fees, facilitating budget planning and project tracking. Final deliverables supports international collaboration and manuscript submission.
Applications
1. Functional Dairy Product Development: Discovering bioactive peptides to support the development of fortified milk powders, whey beverages, and other functional dairy products.
2. Nutritional Mechanism Research: Investigating the potential health benefits of milk-derived peptides in areas such as antihypertension and immune modulation.
3. Process Monitoring and Optimization: Tracking peptide profile changes during thermal treatment, enzymatic hydrolysis, or fermentation to optimize dairy processing.
4. Breed and Geographic Traceability: Identifying source-specific peptides to trace dairy origin and support raw material quality control.
5. Dairy Safety and Label Evaluation: Detecting peptides related to bioactivity or allergenicity for risk assessment and labeling verification.
FAQs
Q1: Is the Milk Peptidomics Analysis Service compatible with fermented dairy products or whey powders?
A: Yes. We support various sample types including skim milk, pasteurized milk, yogurt, whey powder, and infant formula. Each has a dedicated sample preparation protocol.
Q2: Are the deliverables suitable for publication or patent application?
A: Absolutely. We provide comprehensive data packages including raw MS files, quantitative tables, functional annotations, and visualizations, all suitable for preparing SCI manuscripts or technical documentation.
Sample Submission Suggestions
| Sample Type | Recommended Amount | Handling Notes | Shipping Condition |
| Liquid dairy | ≥20 mL | Skim before freezing | Ship at -80°C |
| Powdered dairy | ≥1 g | Keep dry and sealed | Ship at room temp |
| Fermented milk | ≥10 mL | Specify strains and process info | Ship on dry ice |
For special sample types, please contact us for feasibility assessment. Sample pretreatment services are also available.
Deliverables
1. Raw MS data files (.raw/.mzML)
2. Peptide identification and quantification tables (with PTM info)
3. Differential expression and functional annotation reports
4. Multi-dimensional visualizations (heatmaps, volcano plots, pathway maps)
5. Technical notes and experimental parameters
6. Final project summary report
Milk peptidomics is a powerful and practical tool for functional food development and nutrition research. MtoZ Biolabs, backed by state-of-the-art mass spectrometry platforms and multi-omics capabilities, is committed to providing reliable, professional, and efficient Milk Peptidomics Analysis Service for researchers, food companies, and developers of functional formulations. Contact us to obtain a technical proposal, sample submission guide, or personalized service plan—let’s advance nutritional science together.
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