How to Use the GO Database to Find a Gene's Function, Cellular Localization, and Involved Biological Processes?
First, visit the official Gene Ontology (GO) database website and enter the gene name or ID in the search box. The GO database supports common names, aliases, or specific database IDs. After submitting the search, the database will display detailed information about the gene, including an overview, functional description, cellular location, and involved biological processes.
Gene function usually describes the biochemical activity of the protein or RNA encoded by the gene, such as enzymatic activity or binding properties.
The cellular localization section describes where the gene product is located within the cell. For example, it may be found in the nucleus, mitochondria, or cell membrane.
The biological processes section generally shows the metabolic pathways, signal transduction, cell cycle regulation, and other processes the gene participates in.
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