Glycoprotein Analysis Service

Glycosylation modification not only affects the spatial conformation, biological activity, transport, and localization of proteins, but also plays a crucial role in specific biological processes such as molecular recognition, cell communication, and signal transduction.

 

With the rapid development of protein drugs, monoclonal antibody (mAb) drugs develope rapidly. The glycosylation of mAb drugs has varying degrees of influence on the stability, efficacy, and safety of mAb. Therefore, comprehensive characterization of glycosylation modification is of great significance. For mAb drugs, macromolecular protein drugs, it is essential to evaluate their primary or secondary structure that can affect their efficacy and safety. Hence, qualitative and quantitative studies of glycosylation modifications of mAb drugs are crucial for drug research and development, improvement, and safe use.

 



Gashash, E. A. et al. J Proteome Res. 2017.

Figure 1. Glycoprotein Analysis Service by MtoZ Biolabs

 

Services at MtoZ Biolabs

1. Glycan Type Analysis

2. Glycosylation Site Analysis

3. Glycosylation Sites and Glycoform Analysis