Genome Sequencing Service

    Genome sequencing refers to the comprehensive and high-accuracy determination of an organism’s entire DNA sequence, identifying the precise order of nucleotides across the genome. This foundational technology not only reveals gene locations, structures, and functions but also elucidates complex regulatory networks—serving as a cornerstone of modern life science research.

     

    Since the introduction of Sanger sequencing (first-generation sequencing), the field has undergone transformative advancements. Second-generation sequencing (NGS) brought high-throughput, cost-effective, and parallelized analysis to the forefront. More recently, third-generation technologies (e.g., SMRT and Nanopore) have enabled single-molecule, long-read sequencing, offering improved resolution in repetitive and structurally complex regions and expanding the applicability of genome sequencing across broader biological contexts.

     

    MtoZ Biolabs offers high-coverage, high-fidelity Genome Sequencing Service across species—from microbes to humans—by leveraging state-of-the-art sequencing platforms including Illumina NovaSeq, PacBio Sequel IIe, and Oxford Nanopore PromethION, delivering fully customized, data-rich outputs tailored to your research goals.

     

    Services at MtoZ Biolabs

    MtoZ Biolabs offers end-to-end genome sequencing solutions encompassing sample processing, library construction, high-throughput sequencing, and advanced data analysis. Our Genome Sequencing Service supports diverse species and study types, including human, microbial, plant, animal, and environmental samples. Depending on project needs, we offer short-read (Illumina) and long-read (PacBio, Nanopore) sequencing strategies. Comprehensive bioinformatics support includes de novo assembly, reference alignment, structural variation detection, and SNP/InDel annotation to ensure depth, accuracy, and interpretability.

     

    Analysis Workflow

     

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    Why Choose MtoZ Biolabs?

    ✅ Exceptional Accuracy: Ultra-low error rates, suitable for precision-driven applications.

    ✅ High Throughput: Efficient processing of large sample cohorts to accelerate research timelines.

    ✅ Comprehensive Coverage: Multi-depth genome coverage enables robust detection of rare variants.

    ✅ Broad Sample Compatibility: Suitable for blood, tissue, cells, and low-input samples.

    ✅ Hybrid Strategy Flexibility: Integrate short- and long-read data to balance resolution and structural insight.

    ✅ Integrated Bioinformatics Pipeline: In-house developed tools for seamless interpretation—from raw data to functional insights.

     

    Applications

    Genome sequencing has become a critical tool across multiple fields of biological and translational research, including:

    · Disease Mechanism Research: Identify genetic mutations and pathogenic variants

    · Personalized Medicine: Predict disease susceptibility and inform treatment strategies

    · Cancer Genomics: Characterize tumor mutation profiles and uncover drug resistance pathways

    · Agricultural Genomics: Locate agronomic traits and optimize crop breeding

    · Microbial Genomics: Analyze virulence factors and antibiotic resistance genes

    · Population & Evolutionary Biology: Investigate genetic diversity and evolutionary lineage

     

    What Could be Included in the Report?

    1. Raw sequencing files and quality control reports

    2. Genome assembly or alignment results

    3. Annotated genome-wide variants (SNPs, INDELs, CNVs, SVs)

    4. Functional annotation and pathway analysis

    5. Visualized reports and summary documentation

     

    With continuous innovation in sequencing technologies and decreasing costs, genome sequencing has evolved from a basic research tool to an engine driving clinical translation and industrial application. MtoZ Biolabs is committed to offering high-throughput, customizable Genome Sequencing Service that empower researchers to achieve high-resolution insights—from base-level decoding to biological interpretation.

     

    In addition to genome sequencing, MtoZ Biolabs also provides a full suite of omics services including Protein SequencingTranscriptome Sequencing and Single-cell Sequencing. Contact us today for tailored project planning and complimentary technical consultation.

     

    Related Services

    Protein Sequencing

    Whole Transcriptome Sequencing Analysis Service

    Single-cell Sequencing Service

    Single Cell Genome Sequencing Service

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